Keenamide A
| Code | Size | Price |
|---|
| TAR-T32372-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T32372-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Keenamide A, a cytotoxic cyclic hexapeptide, exhibits significant activity towards the P-388, A-549, MEL-20, and HT-29 tumor cell lines, but was inactive against the D6 and W2 Plasmodium falciparum malarial clones.
CAS:
177742-52-8
Molecular Weight:
620.81
Purity:
0.98
SMILES:
[H][C@@]12CSC(=N1)[C@H](CC(C)C)NC(=O)[C@H](COC(C)(C)C=C)NC(=O)CNC(=O)[C@]1([H])CCCN1C(=O)[C@@]([H])(NC2=O)[C@@H](C)CC |c:4|
References
Donia MS, Wang B, Dunbar DC, Desai PV, Patny A, Avery M, Hamann MT. Mollamides B and C, Cyclic hexapeptides from the indonesian tunicate Didemnum molle. J Nat Prod. 2008 Jun;71(6):941-5. doi: 10.1021/np700718p. Epub 2008 Jun 11. PubMed PMID: 18543965; PubMed Central PMCID: PMC2651694.
Wesson KJ, Hamann MT. Keenamide A, a bioactive cyclic peptide from the marine mollusk Pleurobranchus forskalii. J Nat Prod. 1996 Jun;59(6):629-31. PubMed PMID: 8786369.