OPC 18692
| Code | Size | Price |
|---|
| TAR-T33805-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T33805-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
OPC 18692 is a metabolite of Vesnarinone, a positive inotropic drug developed for congestive heart failure.
CAS:
211369-52-7
Formula:
C22H23N3O4
Molecular Weight:
393.44
Purity:
0.98
SMILES:
O=C(C1=CC=C(OC)C(OC)=C1)N2C=CN(C3=CC=C4NC(=O)CCC4=C3)CC2
References
Wandel C, Lang CC, Cowart DC, Girard AF, Bramer S, Flockhart DA, Wood AJ. Effect of CYP3A inhibition on vesnarinone metabolism in humans. Clin Pharmacol Ther. 1998 May;63(5):506-11. PubMed PMID: 9630823.
Sekar KS, Bramer SL. Extended application of an LC-MS/MS method for the analysis of vesnarinone and its metabolites in human urine and dialysate fluid. J Pharm Biomed Anal. 2003 Nov 24;33(4):711-7. PubMed PMID: 14623597.
Frye RF, Tammara B, Cowart TD, Bramer SL. Effect of disulfiram-mediated CYP2E1 inhibition on the disposition of vesnarinone. J Clin Pharmacol. 1999 Nov;39(11):1177-83. PubMed PMID: 10579149.