Sceptrin
| Code | Size | Price |
|---|
| TAR-T34564-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34564-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Sceptrin is a pyrrole-imidazole alkaloid that is naturally produced by various marine sponges.
CAS:
79703-25-6
Molecular Weight:
693.22
Purity:
0.98
SMILES:
O=C(C1=CC(Br)=CN1)NC[C@H]2[C@H](C3=CN=C(N3)N)[C@@H](C4=CN=C(N4)N)[C@@H]2CNC(C5=CC(Br)=CN5)=O.Cl.Cl
References
Cipres A, O'Malley DP, Li K, Finlay D, Baran PS, Vuori K. Sceptrin, a marine natural compound, inhibits cell motility in a variety of cancer cell lines. ACS Chem Biol. 2010 Feb 19;5(2):195-202. doi: 10.1021/cb900240k. PubMed PMID: 20030414; PubMed Central PMCID: PMC2825093.
Ma Z, Wang X, Wang X, Rodriguez RA, Moore CE, Gao S, Tan X, Ma Y, Rheingold AL, Baran PS, Chen C. ORGANIC SYNTHESIS. Response to Comment on "Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence". Science. 2015 Jul 10;349(6244):149. doi: 10.1126/science.aaa9626. Epub 2015 Jul 9. PubMed PMID: 26160939; PubMed Central PMCID: PMC4536548.
Ma Z, Wang X, Wang X, Rodriguez RA, Moore CE, Gao S, Tan X, Ma Y, Rheingold AL, Baran PS, Chen C. Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence. Science. 2014 Oct 10;346(6206):219-24. doi: 10.1126/science.1255677. PubMed PMID: 25301624; PubMed Central PMCID: PMC4205478.
Sherman DH, Tsukamoto S, Williams RM. ORGANIC SYNTHESIS. Comment on "Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence". Science. 2015 Jul 10;349(6244):149. doi: 10.1126/science.aaa9349. Epub 2015 Jul 9. PubMed PMID: 26160938; PubMed Central PMCID: PMC4499860.