Quinine sulfate dihydrate
| Code | Size | Price |
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| TAR-TN4883-1mL | 1 mL * 10 mM (in DMSO) | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Quinine sulfate dihydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
CAS:
6119-70-6
Molecular Weight:
818.97
Purity:
0.9985
SMILES:
O[C@@H]([C@@]1([H])N2C[C@@H]([C@](CC2)([H])C1)C=C)C3=CC=NC4=C3C=C(OC)C=C4.O=S(O)(O)=O.O[C@@H]([C@@]5([H])N6C[C@@H]([C@](CC6)([H])C5)C=C)C7=CC=NC8=C7C=C(OC)C=C8.O.O.O.O
References
Thaithong S, et al. Susceptibility of Plasmodium falciparum to five drugs: an in vitro study of isolates mainly from Thailand. Trans R Soc Trop Med Hyg. 1983;77(2):228-31.
THURSTON JP. The action of antimalarial drugs in mice infected with Plasmodium berghei. Br J Pharmacol Chemother. 1950 Sep;5(3):409-16.