AdipoGen Life Sciences

anti-ST2 (human), mAb (ST33868)

Product Code:
 
AG-20A-0044
Product Group:
 
Primary Antibodies
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
ST33868
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Blue Ice
Storage:
 
Short term: +4°C. Long term: -20°C
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Immunohistochemical staining of human tissue using anti-ST2 (human), mAb (ST33868) (Prod. No. AG-20A-0044) at 1:100 dilution. A. Immunoperoxidase staining (cytoplasmic) of formalin-fixed, paraffin-embedded human heart (100x, brown colour). B.
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Immunohistochemical staining of human tissue using anti-ST2 (human), mAb (ST33868) (Prod. No. AG-20A-0044) at 1:100 dilution. A. Immunoperoxidase staining (cytoplasmic) of formalin-fixed, paraffin-embedded human heart (100x, brown colour). B.

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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
Interleukin-1 Receptor-like 1; IL-1 Receptor-like 1; IL1RL1; IL-33 Receptor; Interleukin-33 Receptor
Concentration:
1mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Recombinant human soluble ST2.
Long Description:
Monoclonal Antibody. Recognizes human ST2. Isotype: Mouse IgG1kappa. Clone: ST33868. Applications: ELISA, IHC, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. The ST2 gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
NCBI, Uniprot Number:
Q01638
Package Type:
Plastic Vial
Product Description:
The ST2 gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
Specificity:
Recognizes human ST2.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.

References

Experimentally induced psoriatic lesions associate with rapid but transient decrease in interleukin-33 immunostaining in epidermis: M.M. Suttle, et al.; Acta Derm. Venereol. 95, 536 (2015)