IL-1beta (human) (rec.) (untagged)
| Code | Size | Price |
|---|
| AG-40B-0023-C010 | 10 ug | £170.00 |
Quantity:
| AG-40B-0023-3010 | 3 x 10 ug | £330.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: E.coli
Regulatory Status: RUO
Target Species: Human
Shipping:
Blue Ice
Storage:
-20°C
Further Information
Alternate Names/Synonyms:
Interleukin-1beta; IL-1F2
Biological Activity:
Activates the NF-kappaB with an ED50 of <5ng/ml.
Concentration:
0.1mg/ml after reconstitution.
EClass:
32160000
Endotoxin:
<0.1EU/µg purified protein (LAL test; Lonza).
Form (Short):
liquid
Formulation:
Lyophilized. Contains PBS.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.
Long Description:
Protein. Human IL-1beta (aa 117-269) is untagged. Source: E. coli. Endotoxin content: <0.1EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds to human IL-1R. Purity: >95% (SDS-PAGE). IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1beta in most situations requires the inflammasome complex to be cleaved and secreted.
Molecular Weight:
~17kDa (SDS-PAGE)
NCBI, Uniprot Number:
P01584
Package Type:
Plastic Vial
Product Description:
IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1beta in most situations requires the inflammasome complex to be cleaved and secreted.
Purity:
>95% (SDS-PAGE)
Sequence:
Human IL-1beta (aa 117-269) is untagged.
Source / Host:
E. coli
Specificity:
Binds to human IL-1R.
TAGs:
no TAG
Transportation:
Non-hazardous
UNSPSC Category:
Interleukins
UNSPSC Number:
41116127
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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