Adiponectin (human) ELISA Kit (Twin Plex)

AdipoGen Life Sciences
Product Code: AG-45A-0001Y
Product Group: ELISA Kits
CodeSizePrice
AG-45A-0001YEK-KI0196 wells£410.00
Quantity:
AG-45A-0001YTP-KI012 x 96 wells£710.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
Blue Ice
Storage:
4deg;C

Images

1 / 1
Standard Curve

Standard Curve

Further Information

Alternate Names/Synonyms:
ACRP30; AdipoQ; apM1; GBP28; Adipocyte complement related protein of 30kDa
Assay Type:
Sandwich
Detection Type:
Colorimetric
EClass:
32160000
Form (Short):
liquid
Handling Advice:
After standard reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Plate and reagents should reach room temperature before use.
Long Description:
ELISA Assay. Detects human adiponectin. Does not cross-react with mouse adiponectin, rat adiponectin, human resistin, human RELM-beta or human leptin. Colorimetric assay. Sample Types: Cell Culture Supernatant, Plasma, Serum, Urine. Range: 0.5 to 32ng/ml. Sensitivity: 100pg/ml. Adiponectin is a promising biomarker of insulin resistance and type 2 diabetes mellitus (T2DM) but also as a potential target for management of the metabolic syndrome. It is a very robust marker that is not prone to degradation or acute inflammatory challenges, is present in relatively high concentrations in the peripheral circulation, and can be collected by a variety of methods. The benefits of using adiponectin assays in clinical settings include, (a) prediction of risk of diabetes and metabolic status and (b) providing a tool to monitor metabolic improvements. Adiponectin exerts anti-atherogenic and anti-inflammatory properties and may be important as a biomarker for obesity-related cardiovascular disease (CVD). New findings showed urinary adiponectin excretion as an independent new biomarker of microvascular and macrovascular damage in T2DM and suggested it as a very promising tool for early cardiovascular disease risk assessment. Adiponectin serum level was also described as a good biomarker of colorectal adenoma, this being related to the positive correlation between obesity and increased risk of cancer at various sites (colorectal, breast, prostate and endometrium).
NCBI, Uniprot Number:
Q15848
Package Type:
Box
Product Description:
Adiponectin [ACRP30; AdipoQ] is a promising biomarker of insulin resistance and type 2 diabetes mellitus (T2DM) but also as a potential target for management of the metabolic syndrome. It is a very robust marker that is not prone to degradation or acute inflammatory challenges, is present in relatively high concentrations in the peripheral circulation, and can be collected by a variety of methods. The benefits of using adiponectin assays in clinical settings include, (a) prediction of risk of diabetes and metabolic status and (b) providing a tool to monitor metabolic improvements. Adiponectin exerts anti-atherogenic and anti-inflammatory properties and may be important as a biomarker for obesity-related cardiovascular disease (CVD). New findings showed urinary adiponectin excretion as an independent new biomarker of microvascular and macrovascular damage in T2DM and suggested it as a very promising tool for early cardiovascular disease risk assessment. Adiponectin serum level was also described as a good biomarker of colorectal adenoma, this being related to the positive correlation between obesity and increased risk of cancer at various sites (colorectal, breast, prostate and endometrium).
Range:
0.5 to 32ng/ml
Sample Type:
Cell Culture Supernatant, Plasma, Serum, Urine
Sensitivity:
100pg/ml
Specificity:
Detects human adiponectin. Does not cross-react with mouse adiponectin, rat adiponectin, human resistin, human RELM-beta or human leptin.
Transportation:
Non-hazardous
UNSPSC Category:
ELISA Kits
UNSPSC Number:
41116126
Use & Stability:
12 months after the day of manufacturing. See expiry date on ELISA Kit box.

References

Plasma adiponectin levels in postmenopausal women with or without long-term hormone therapy: J. Ima; Maturitas 54, 65 (2006) | Association between hypoadiponectinemia and cardiovascular risk factors in nonobese healthy adults. J.A. Im, et al.; Metabolism 55, 1546 (2006) | Relationship of serum adiponectin and resistin levels with breast cancer risk: J.H. Kang, et al.; J. Korean Med. Sci. 22, 117 (2007) | Improved insulin sensitivity and adiponectin level after exercise training in obese Korean youth: E.S. Kim, et al.; Obesity 15, 3023 (2007) | Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations: T. Yasui, et al.; Clin. Chim. Acta 386, 69 (2007) | Crosstalk between high-molecular-weight adiponectin and T-cadherin during liver fibrosis development in rats: K. Asada, et al.; Intl. J. Mol. Med. 20, 725 (2007) | Retinol binding protein 4, low birth weight-related insulin resistance and hormonal contraception: A. Zugaro, et al.; Endocrine 32, 166 (2007) | Leptin is Associated with Endothelial Dysfunction in Healthy Obese Premenopausal Women: K. Kwon, et al.; Kor. Circ. J. 37, 251 (2007) | Correlation between estrogens and serum adipocytokines in premenopausal and postmenopausal women: S.C. Hong, et al.; Menopause 14, 835 (2007) | Transgenic mice expressing nuclear sterol regulatory element-binding protein 1c in adipose tissue exhibit liver histology similar to nonalcoholic steatohepatitis: H. Nakayama, et al.; Metabolism 56, 470 (2007) | Insulin-sensitizing effects of exercise on Adiponectin and Retinol Binding Protein-4 concentrations in young and middle-aged women: S. Lim, et al.; J. Clin. Endocrinol. Metab. 93, 2263 (2008) | Retinol Binding Protein-4 elevation is associated with serum TSH level independently of obesity in elderly subjects with normal glucose tolerance: S. H. Choi, et al.; J. Clin. Endocrinol. Metab. 93, 2313 (2008) | Fat in liver/muscle correlates more strongly with insulin sensitivity in rats than abdominal fat: S. Lim, et al.; Obesity 17, 188 (2008) | Obesity-related promotion of aberrant crypt foci in DMH-treated obesis Zucker rats correlates with dyslipidemia rather than hyperinsulinemia: T.C. Koch, et al.; Eur. J. Nutr. 47, 161 (2008) | Changes of Serum Adiponectin Levels in Murine Experimental Sparganosis: H.J. Yang; Kor. J. Parasitol. 46, 91 (2008) | Mas Deficiency in FVB/N mice produces marked changes in lipid and glycemic metabolism: S.H. Santos, et al.; Diabetes 57, 340 (2008) | Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet: I. Shai, et al.; N. Engl. J. Med. 359, 229 (2008) | Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration: P. Polak, et al.; Cell Metab. 8, 399 (2008) | Serum Adipocyte Fatty Acid-Binding Protein Levels Are Associated With Nonalcoholic Fatty Liver Disease in Type 2 Diabetic Patients: J.H. Koh, et al.; Diab. Care 32, 147 (2009) | Elevated serum g-glutamyltransferase levels are independently associated with insulin resistance in non-diabetic subjects: J.Y. Shin, et al.; Diabetes Res. Clin. Pract. 84, 152 (2009) | The Lou/C rat: A model of spontaneous food restriction associated with improved insulin sensitivity and decreased lipid storage in adipose tissue: C. Veyrat-Durebex, et al.; Am. J. Physiol. Endocrinol. Metab. 296, E1120 (2009) | MicroRNA Expression in Human Omental and Subcutaneous Adipose Tissue: N. Kl?ting, et al.; PLoS One 4, e4699 (2009) | Adipokines and Systemic Lupus Erythematosus: Relationship with Metabolic Syndrome and Cardiovascular Disease Risk Factors: M. Vadacca, et al.; J. Rheumatol. 36, 295 (2009) | Relationship between serum adipocytokine levels and metabolic syndrome in menopausal women: H.T. Park, et al.; Gynecol. Endocrinol. 25, 27 (2009) | Circuit resistance exercise improves glycemic control and adipokines in females with type 2 diabetes mellitus: S. Kang, et al.; JSSM 8, 682 (2009) | Relationship between genotype and serum levels of adipokines and bone mineral density in type 2 diabetes mellitus patients: K. Mirzaei, et al.; Iran. J. Diab. Lip. Dis. 8, 77 (2009) | Combined Impact of Adiponectin and Retinol-binding Protein 4 on Metabolic Syndrome in Elderly People: The Korean Longitudinal Study on Health and Aging: S. Lim, et al.; Obesity 18, 826 (2010) | Body weight control by a high-carbohydrate/low-fat diet slows the progression of diabetic kidney damage in an obese, hypertensive, type 2 diabetic rat model: S. Ohtomo, et al.; J. Obes. 2010, 136502 (2010) | Combined effects of body mass index and cardio/respiratory fitness on serum vaspin concentrations in Korean young men: J.K. Chou, et al.; Eur. J. Appl. Physiol. 108, 347 (2010) | Adiponectin, Resistin and Leptin Response to Dietary Intervention in Diabetic Nephropathy: L. Kozlowska, et al.; J. Ren. Nutr. 20, 255 (2010) | Possible involvement and the mechanisms of excess trans-fatty acid consumption in severe NAFLD in mice: N. Obara, et al.; J. Hepatol. 53, 326 (2010) | Improved lipid and glucose metabolism in transgenic rats with increased circulating angiotensin-(1-7): S.H. Santos, et al.; Arterioscler. Thromb. Vasc. Biol. 30, 953 (2010) | Dietary sphingolipids ameliorate disorders of lipid metabolism in Zucker fatty rats: K. Yunoki, et al.; J. Agric. Food Chem. 58, 7030 (2010) | Association of insulin resistance with anti-Mullerian hormone levels in women without polycystic ovary syndrome (PCOS): H.T. Park, et al.; Clin. Endocrinol. (Oxf) 72, 26 (2010) | Effects of body composition, leptin, and adiponectin on bone mineral density in prepubertal girls: Y.J. Rhie, et al.; J. Korean Med. Sci. 25, 1187 (2010) | Adiponectin is produced by lymphocytes and is a negative regulator of granulopoiesis: L.J. Crawford, et al.; J. Leukoc. Biol. 88, 807 (2010) | A nonthiazolidinedione peroxisome proliferator-activated receptor / dual agonist CG301360 alleviates insulin resistance and lipid dysregulation in db/db mice: H.W. Jeong, et al.; Mol. Pharmacol. 78, 877 (2010) | Adipokine pattern in subjects with impaired fasting glucose and impaired glucose tolerance in comparison to normal glucose tolerance and diabetes: A. Tonjes, et al.; PLoS One 5, e13911 (2010) | Body weight control by a high-carbohydrate/low-fat diet slows the progression of diabetic kidney damage in an obese, hypertensive, type 2 diabetic rat model: S. Ohtomo, et al.; J. Obes. 2010, 136502 (2010) | Serum levels of CK18 M30 and leptin are useful predictors of steatohepatitis and fibrosis in paediatric NAFLD: E. Fitzpatrick, et al.; J. Pediatr. Gastroenterol. Nutr. 51, 500 (2010) | Resistin, adiponectin and visfatin; can adipocytokines predict gestational diabetes mellitus and early post partum metabolic syndrome?: A. Hossein-nezhad, et al.; Iran. J. Diab. Lip. Dis. 9, 6 (2010) | Combined effects of body mass index and cardio/respiratory fitness on serum vaspin concentrations in Korean young men: J.K. Cho, et al.; Eur. J. Appl. Physiol. 108, 347 (2010) | A nonthiazolidinedione peroxisome proliferator-activated receptor alpha/gamma dual agonist CG301360 alleviates insulin resistance and lipid dysregulation in db/db mice: H.W. Jeong, et al.; Mol. Pharmacol. 78, 877 (2010) | Organotypic culture of human bone marrow adipose tissue: K. Uchihashi, et al.; Pathol. Int. 60, 259 (2010) | ADIPOQ SNP45 associated with lean body mass in physically active normal weight adolescent girls: C.L. Passariello, et al.; Am. J. Hum. Biol. 22, 813 (2010) | Adiponectin, resistin and leptin response to dietary intervention in diabetic nephropathy: L. Koz?owska, et al.; J. Ren. Nutr. 20, 255 (2010) | Body weight control by a high-carbohydrate/low-fat diet slows the progression of diabetic kidney damage in an obese, hypertensive, type 2 diabetic rat model: S. Ohtomo, et al.; J. Obes. 2010, 136502 (2010) | Adipocytokines and bone mineral density in adolescent female athletes: R. Gruodyte, et al.; Acta Paediatr. 99, 1879 (2010) | Effect of green tea extract on bone turnover markers in type 2 diabetic patients; A double- blind, placebo-controlled clinical trial study: K. Mirzaei, et al.; DARU J. Pharm. Sci. 17 (Suppl 1), 38 (2010) | Phenotypic and genetic variation in leptin as determinants of weight regain: G. Erez, et al.; Int. J. Obes. (Lond) 35, 785 (2011) | Apolipoprotein B/A1 ratio is associated with free androgen index and visceral adiposity and may be an indicator of metabolic syndrome in male children and adolescents: Y.H. Lee, et al.; Clin. Endocrinol. (Oxf) 74, 579 (2011) | Circulating Nampt and RBP4 levels in patients with carotid stenosis undergoing carotid endarterectomy (CEA): G. Aust, et al.; Clin. Chim. Acta 412, 1195 (2011) | Serum visfatin is associated with type 2 diabetes mellitus independent of insulin resistance and obesity: A. Esteghamati, et al.; Diabetes Res. Clin. Pract. 91, 154 (2011) | Role of AMP-activated Protein Kinase and Adiponectin during Development of Hepatic Steatosis in High-fat Diet-induced Obesity in Rats: S.K. Ha, et al.; J. Comp. Pathol. 145, 88 (2011) | Adipokines, insulin resistance, metabolic syndrome, and breast cancer recurrence: a cohort study: S.W. Oh, et al.; Breast Cancer Res. 13, R34 (2011) | Plasma visfatin and adiponectin concentrations in physically active adolescent girls: relationships with insulin sensitivity and body composition variables: J. Jurimae, et al.; JPEM 24, 419 (2011) | Relationship between inflammation biomarkers, antioxidant vitamins, and bone mineral density in patients with metabolic syndrome: Y. Lee, et al.; Nutr. Res. Pract. 5, 150 (2011) | Clinically silent adrenal adenomas - their relation to the metabolic syndrome and to GNB3 C825T gene polymorphism: I. Lazurova, et al.; Wien. Klin. Wochenschr. 123, 618 (2011) | Optimal cut points of waist circumference (WC) and visceral fat area (VFA) predicting for metabolic syndrome (MetS) in elderly population in the Korean Longitudinal Study on Health and Aging (KLoSHA): S. Lim, et al.; Arch. Gerontol. Geriatr. 54, e29(2012) | Effects of aerobic exercise training on C1q tumor necrosis factor alpha-related protein isoform 5 (myonectin): association with insulin resistance and mitochondrial DNA density in women: S. Lim, et al.; J. Clin. Endocrinol. Metab. 97, E88 (2012) | Genetic effects of adiponectin single nucleotide polymorphisms on the clustering of metabolic risk factors in young Korean adults: J.Y. Lee, et al.; Eur. J. Appl. Physiol. 112, 623 (2012) | The effects of detraining on blood adipokines and antioxidant enzyme in Korean overweight children: J. Woo, et al.; Eur. J. Pediatr. 171, 235 (2012) | Plasma adiponectin elevation in elderly individuals with subsyndromal depression: H.G. Jeong, et al.; Psychoneuroendocrinol. 37, 948 (2012) | Leptin, adiponectin and vascular stiffness parameters in women with systemic lupus erythematosus: M. Vadacca, et al.; Intern. Emerg. Med. 8, 705 (2013) | Change of coronary flow velocity during the cold pressor test is related to endothelial markers in subjects with chest pain and a normal coronary angiogram: H.J. Hwang, et al.; Clin. Cardiol. 35, 119 (2012) | Efficacy and safety of ginsam, a vinegar extract from Panax ginseng, in type 2 diabetic patients: Results of a double-blind, placebo-controlled study: J.W. Yoon, et al.; J. Diabet. Inv. 3, 309 (2011) | The normoglycemic first-degree relatives of patients with type 2 diabetes mellitus have low circulating omentin-1 and adiponectin levels: S. Akbarzadeh, et al.; Cytokine 58, 295 (2012) | High-sensitivity C-reactive protein is independently associated with arterial stiffness in women with metabolic syndrome: E.G. Oh, et al.; J. Cardiovasc. Nurs. 27, 61 (2012) | Chitooligosaccharide ameliorates diet-induced obesity in mice and affects adipose gene expression involved in adipogenesis and inflammation: E.H. Choi, et al.; Nutr. Res. 32, 218 (2012) | AMPK activation with glabridin ameliorates adiposity and lipid dysregulation in obesity: J.W. Lee, et al.; J. Lipid. Res. 53, 1277 (2012) | The role of leptin and its short-form receptor in inflammation in db/db mice infused with peritoneal dialysis fluid: J.C. Leung, et al.; Nephrol. Dial. Transplant. 27, 3119 (2012) | The Value of Visfatin in the Prediction of Metabolic Syndrome: A Multi-Factorial Analysis: A. Esteghamati, et al.; J. Cardiovasc. Transl. Res. 5, 541 (2012) | Carotid intima media thickness, brachial flow mediated dilation and previous history of gestational diabetes mellitus: H. Fakhrzadeh, et al.; J. Obstet. Gynaecol. Res. 38, 1057 (2012) | Progranulin as a Prognostic Biomarker for Breast Cancer Recurrence in Patients Who Had Hormone Receptor-Positive Tumors: A Cohort Study: D.H. Koo, et al.; PLoS One 7, e39880 (2012) | Mitochondrial DNA copy number in peripheral blood is associated with femoral neck bone mineral density in postmenopausal women: J.H. Kim & D.C. Lee; J. Rheumatol. 39, 1465 (2012) | Low Serum Adiponectin Levels in Korean Children with a Family History of Type 2 Diabetes Mellitus: Y.J. Oh, et al.; Horm. Res. Paediatr. 77, 382 (2012) | Comparison of regional body composition and its relation with cardiometabolic risk between BMI-matched young and old subjects: Y. Lee, et al.; Atherosclerosis 224, 258 (2012) | The framingham risk score, diet, and inflammatory markers in Korean men with metabolic syndrome: C. Sohn, et al.; Nutr. Res. Pract. 6, 246 (2012) | Association between obesity and asthma in the elderly population: potential roles of abdominal subcutaneous adiposity and sarcopenia: W.J. Song, et al.; Ann. Allergy Asthma Immunol. 109, 243 (2012) | Omentin-1, visfatin and adiponectin levels in relation to bone mineral density in Iranian postmenopausal women: M. Tohidi, et al.; Bone 51, 876 (2012) | A 12-week after-school physical activity programme improves endothelial cell function in overweight and obese children: a randomised controlled study: J.H. Park, et al.; BMC Pediatr. 12, 111 (2012) | Adiponectin, leptin and lipid profiles evaluation in oral contraceptive pill consumers: S. Fallah, et al.; Arch. Gynecol. Obstet. 285, 1747 (2012) | Dietary intervention induces flow of changes within biomarkers of lipids, inflammation, liver enzymes, and glycemic control: R. Golan, et al.; Nutrition 28, 131 (2012) | Metabolic Syndrome is Associated with Low Adiponectin Level and Increased Insulin Resistance in Apparently Healthy Koreans: K.H. Yoo, et al.; Korean J. Obes. 21, 175 (2012) | Gastrectomy for Early Gastric Cancer is Associated with Decreased Cardiovascular Mortality in Association with Postsurgical Metabolic Changes:Y.H. Lee, et al.; Ann. Surg. Oncol. 20, 1250 (2012) | Implication of Progranulin and C1q/TNF-Related Protein-3 (CTRP3) on Inflammation and Atherosclerosis in Subjects with or without Metabolic Syndrome: H.J. Yoo, et al.; PLOS One 8, e55744 (2013) | Effects of a Combined Aerobic and Resistance Exercise Program on C1q/TNF-Related Protein-3 (CTRP-3) and CTRP-5 Levels: H.Y. Choi, et al.; Diabetes Care 36, 3321 (2013) | Urinary adiponectin concentration is positively associated with micro- and macro-vascular complications: W.S. Jeon, et al.; Cardiovasc. Diabetol. 12, 137 (2013) | Effect of weight reduction following bariatric surgery on serum visfatin and adiponectin levels in morbidly obese subjects: M.J. Hosseinzadeh-Attar, et al.; Obes. Facts 6, 193 (2013) | Implications of C1q/TNF-related protein-3 (CTRP-3) and progranulin in patients with acute coronary syndrome and stable angina pectoris: K.M. Choi, et al.; Cardiovasc. Diabetol. 13, 14 (2014) | Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation: G. Flehmig, et al.; PLos One 9, e99785 (2014)

Related Products

Product NameProduct CodeSupplier