Polyketomycin
| Code | Size | Price |
|---|
| BVT-0033-M001 | 1 mg | £160.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
20°C
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Antibiotic K99-5147
Appearance:
Orange to dark brown solid.
CAS:
200625-47-4
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS07,GHS08
Handling Advice:
Protect from light when in solution.
Hazards:
H302, H312, H319, H332, H351
InChi:
InChI=1S/C44H48O18/c1-16-9-10-17(2)33(47)28(16)41(53)62-39-21(6)59-27(15-42(39,7)54)60-24-11-12-26(58-20(24)5)61-40-36(50)30(19(4)45)37(51)44(56)38(52)31-22(14-43(40,44)55)18(3)29-32(35(31)49)23(46)13-25(57-8)34(29)48/h9-10,13,20-21,24,26-27,39-40,45,47,49,54-56H,11-12,14-15H2,1-8H3/b30-19+/t20-,21+,24+,26+,27+,39-,40-,42-,43-,44-/m1/s1
InChiKey:
OWRCRVABZYJUES-FLJLGRLJSA-N
Long Description:
Chemical. CAS: 200625-47-4. Formula: C44H48O18. MW: 864.8. Isolated from Streptomyces sp. Tetracyclic quinone glycoside. Antibacterial and antimalarial. Antitumor compound.
MDL:
N/A
Molecular Formula:
C44H48O18
Molecular Weight:
864.8
Package Type:
Plastic Vial
Precautions:
P201, P261, P270, P281, P301, P312, P302, P352, P405
Product Description:
Tetracyclic quinone glycoside. Antibacterial and antimalarial. Antitumor compound.
Purity:
>98% (HPLC)
Signal Word:
Warning
SMILES:
[H][C@@]1(CC[C@H](O[C@@]2([H])C[C@@](C)(O)[C@H](OC(=O)C3=C(C)C=CC(C)=C3O)[C@H](C)O2)[C@@H](C)O1)O[C@@H]1C(=O)C(=C(C)O)C(=O)[C@@]2(O)C(=O)C3=C(C[C@@]12O)C(C)=C1C(=O)C(OC)=CC(=O)C1=C3O
Solubility Chemicals:
Soluble in DMSO, methanol or acetone.
Source / Host:
Isolated from Streptomyces sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
References
Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. I. Taxonomy, production, isolation, physico-chemical properties and biological activities: I. Momose, et al.; J. Antibiot. 51, 21 (1998) | Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. II. Structure determination: I. Momose, et al.; J. Antibiot. 51, 26 (1998) | Biosynthesis of polyketomycin produced by Streptomyces diastatochromogenes T? 6028: T. Paululat, et al.; J. Antibiot. 52, 96 (1999) | In vitro antimalarial activities of the microbial metabolites: K. Otoguro, et al.; J. Antibiot. 56, 322 (2003) | Synthesis of the polyketomycin disaccharide: D.S. Micalizzi, et al.; Tetrahedron: Asymmetry 14, 3183 (2003)