Chrysomycin B
| Code | Size | Price |
|---|
| BVT-0100-C250 | 250 ug | £160.00 |
Quantity:
| BVT-0100-M001 | 1 mg | £375.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
20°C
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Chrysomycin M; Virenomycin M
Appearance:
Yellow to greenish solid.
CAS:
83852-56-6
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07,GHS08
Handling Advice:
Protect from light.
Hazards:
H302, H312, H319, H351
InChi:
InChI=1S/C27H28O9/c1-11-8-15-19(17(9-11)33-4)14-10-18(34-5)21-16(28)7-6-13(20(21)22(14)36-26(15)31)23-25(30)27(3,32)24(29)12(2)35-23/h6-10,12,23-25,28-30,32H,1-5H3/t12-,23+,24+,25+,27-/m1/s1
InChiKey:
BJPYMDSMDBCKEP-QSMCFSHASA-N
Long Description:
Chemical. CAS: 83852-56-6. Formula: C27H28O9. MW: 496.5. Isolated from Streptomyces sp. Antibiotic. Topoisomerase II inhibitor. Mediates a unique cross-linking reaction between DNA and histidine H3. Anti-neoplastic. Photosensitizing compound. Antitumor compound against human cell lines. Less potent than chrysomycin A (Prod. No. BVT-0099).
MDL:
MFCD07370132
Molecular Formula:
C27H28O9
Molecular Weight:
496.5
Package Type:
Plastic Vial
Precautions:
P201, P270, P281, P301, P312, P302, P352, P405
Product Description:
Antibiotic. Topoisomerase II inhibitor. Mediates a unique cross-linking reaction between DNA and histidine H3. Anti-neoplastic. Photosensitizing compound. Antitumor compound against human cell lines. Less potent than chrysomycin A (Prod. No. BVT-0099).
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
COC1=CC2=C(OC(=O)C3=CC(C)=CC(OC)=C23)C2=C1C(O)=CC=C2[C@@H]1OC(C)[C@H](O)[C@](C)(O)C1O
Solubility Chemicals:
Soluble in DMSO or dimethylformamide; slightly soluble in 100% ethanol or methanol.
Source / Host:
Isolated from Streptomyces sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
References
Chrysomycin: a new antibiotic substance for bacterial viruses: F. Strelitz, et al.; J. Bacteriol. 69, 280 (1955) | The chemistry of the antibiotics chrysomycin A and B. Antitumor activity of chrysomycin A: U. Weiss, et al.; J. Antibiot. 35, 1194 (1982) | Biochemical characterisation of elsamicin and other coumarin-related antitumour agents as potent inhibitors of human topoisomerase II: A. Lorico and B.H. Long; Eur. J. Cancer 29A, 1985 (1993)
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