Elasnin
| Code | Size | Price |
|---|
| BVT-0342-M001 | 1 mg | £150.00 |
Quantity:
| BVT-0342-M005 | 5 mg | £425.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
20°C
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
3,5-Dibutyl-4-hydroxy-6-(6-oxoundecan-5-yl)-2H-pyran-2-one
Appearance:
Tan to brown viscous liquid.
CAS:
68112-21-0
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.Protect from light when in solution.
Hazards:
H302, H319
InChi:
InChI=1S/C24H40O4/c1-5-9-13-17-21(25)18(14-10-6-2)23-19(15-11-7-3)22(26)20(16-12-8-4)24(27)28-23/h18,26H,5-17H2,1-4H3
InChiKey:
SNSPVFCYLPZTRZ-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 68112-21-0. Formula: C24H40O4. MW: 392.6. Isolated from Streptomyces sp. Inhibitor of human leukocyte elastase (IC50 = 1.3 µg/ml), different other elastases and chymotrypsin (IC50 = 82 µg/ml).
MDL:
MFCD01694027
Molecular Formula:
C24H40O4
Molecular Weight:
392.6
Package Type:
Plastic Vial
Precautions:
P270, P280, P301, P312, P305, P351, P338
Product Description:
Inhibitor of human leukocyte elastase (IC50 = 1.3 µg/ml), different other elastases and chymotrypsin (IC50 = 82 µg/ml).
Purity:
>97% (HPLC)
Signal word:
Warning
SMILES:
CCCCCC(=O)C(CCCC)C1=C(CCCC)C(O)=C(CCCC)C(=O)O1
Solubility Chemicals:
Soluble in DMSO (5 mg/ml), methanol (5 mg/ml) or methylene chloride.
Source / Host:
Isolated from Streptomyces sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
References
Elasnin, a new human granulocyte elastase inhibitor produced by a strain of Streptomyces.: S. Omura, et al.; BBRC 83, 704 (1978) | Isolation and characterization of elasnin, a new human granulocyte elastase inhibitor produced by a strain of Streptomyces: H. Ohno, et al.; J. Antibiot. 31, 1116 (1978) | Inhibition of human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin by elasnin and other 4-hydroxy-2-pyrones.: R.W. Spencer, et al.; J. Med. Chem. 28, 1828 (1985) | Inhibition of human sputum elastase by substituted 2-pyrones.: L. Cook, et al.; J. Med. Chem. 30, 1017 (1987)