Aranciamycin
| Code | Size | Price |
|---|
| BVT-0364-C500 | 500 ug | £150.00 |
Quantity:
| BVT-0364-M001 | 1 mg | £245.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
20°C
Storage:
-20°C
Documents
Further Information
Appearance:
Yellow to orange solid.
CAS:
72389-06-1
Class:
6.1
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS06
Hazards:
H301, H311, H319, H332
InChi:
InChI=1S/C27H28O12/c1-9-17(29)21(33)23(36-3)26(38-9)39-22-16-12(24(34)27(2,35)25(22)37-4)8-11-15(20(16)32)19(31)14-10(18(11)30)6-5-7-13(14)28/h5-9,17,21-23,25-26,28-29,32-33,35H,1-4H3/t9-,17+,21+,22+,23?,25?,26-,27+/m0/s1
InChiKey:
PGCZNTNNZCKKFG-XXHKFMCWSA-N
Long Description:
Chemical. CAS: 72389-06-1. Formula: C27H28O12. MW: 544.5. Isolated from Streptomyces echinatus. Antibiotic. Similar to steffimycin. Active against Gram-positive bacteria. Clostridium histolyticum collagenase inhibitor. Antitumor compound.
MDL:
MFCD28898539
Molecular Formula:
C27H28O12
Molecular Weight:
544.5
Package Type:
Plastic Vial
PG:
III
Precautions:
P261, P280, P301, P310, P312, P302, P352, P405
Product Description:
Antibiotic. Similar to steffimycin. Active against Gram-positive bacteria. Clostridium histolyticum collagenase inhibitor. Antitumor compound.
Purity:
>98% (HPLC)
Signal word:
Danger
SMILES:
[H][C@@]1(O[C@H]2[C@H](OC)[C@](C)(O)C(=O)C3=C2C(O)=C2C(=O)C4=C(C=CC=C4O)C(=O)C2=C3)O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]1OC
Solubility Chemicals:
Soluble in DMSO.
Source / Host:
Isolated from Streptomyces echinatus.
Transportation:
Excepted Quantity
UN Nummer:
UN 3462
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
References
Aranciamycin: W. Keller-Schierlein, et al.; Helv. Chim. Acta 53, 779 (1970) | Inhibition of collagenase by aranciamycin and aranciamycin derivatives: M. Bols, et al.; J. Med. Chem. 35, 2768 (1992) | Structure of the anthracycline antibiotic aranciamycin: K. Schmidt-B?se, et al.; Acta Cryst. C 49, 250 (1993) | Cloning and heterologous expression of the aranciamycin biosynthetic gene cluster revealed a new flexible glycosyltransferase: A. Luzhetskyy, et al.; ChemBioChem 8, 599 (2007) | Aranciamycin analogs generated by combinatorial biosynthesis show improved antitumor activity: A. Luzhetskyy, et al.; Appl. Microbiol. Biotechnol. 80, 15 (2008). | Aranciamycin anhydride, a new anthracycline-type antibiotic isolated from Streptomyces sp. T? 6384: J. Nachtigall, et al.; J. Antibiot. 63, 397 (2010) | Aranciamycins I and J, Antimycobacterial Anthracyclines from an Australian Marine-Derived Streptomyces sp.: Z.G. Khalil, et al.; J. Nat. Prod. 78, 949 (2015)
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