anti-CD154 (human), mAb (24-31) (preservative free)
Code | Size | Price |
---|
ANC-353-820-100ug | 100 ug | £243.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: Mouse IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 24-31
Regulatory Status: RUO
Target Species:
- Human
- Monkey
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Flow Cytometry
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
BI
Storage:
+4°C
Documents
Further Information
EClass:
32160000
Form (Short):
liquid
Formulation:
50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
Human sgp39 fusion protein.
Labels - Conjugates:
Preservative Free
Long Description:
Monoclonal Antibody. Isotype: Mouse IgG1. Clone: 24-31. Applications: ELISA, FACS, FUNC (Blocking), IHC, WB. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl Human CD154 (CD40 ligand) is a member of the TNF family and is expressed on the surface of activated T cells. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function. CD154 has been shown to be hyperexpressed by B and T cells in SLE patients. CD154 has been reported to be expressed on vascular endothelial cells, smooth muscle cells and macrophages indicating a possible role for the CD40-CD154 immunoregulatory signaling mechanism during inflammation and immunity in atherogenesis.
Package Type:
Plastic Vial
Product Description:
Human CD154 (CD40 ligand) is a member of the TNF family and is expressed on the surface of activated T cells. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function. CD154 has been shown to be hyperexpressed by B and T cells in SLE patients. CD154 has been reported to be expressed on vascular endothelial cells, smooth muscle cells and macrophages indicating a possible role for the CD40-CD154 immunoregulatory signaling mechanism during inflammation and immunity in atherogenesis.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at +4°C.
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