Penicillide
Product Code: AG-CN2-0122
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0122-C250 | 250 ug | £60.00 |
Quantity:
| AG-CN2-0122-M001 | 1 mg | £160.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Vermixocin A; Antibiotic AS 186A; Antibiotic MC 140
Appearance:
Off-white solid.
CAS:
55303-92-9
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.
Hazards:
H302, H312, H332
InChi:
InChI=1/C21H24O6/c1-11(2)7-15(22)14-5-6-17-18(20(14)25-4)21(24)26-10-13-8-12(3)9-16(23)19(13)27-17/h5-6,8-9,11,15,22-23H,7,10H2,1-4H3
InChiKey:
UOWGLBYIKHMCIS-UHFFFAOYAA
Long Description:
Chemical. CAS: 55303-92-9. Formula: C21H24O6. MW: 372.4. Isolated from Penicillium sp. Plant growth inhibitor. Acyl-CoA-cholesterol acyltransferase (ACAT) inhibitor. Anticancer compound. Cytotoxic. Non-peptidic oxytocin receptor antagonist. Calpain inhibitor.
Molecular Formula:
C21H24O6
Molecular Weight:
372.4
Package Type:
Vial
Precautions:
P261, P301, P312, P302, P352, P304, P340
Product Description:
Plant growth inhibitor [1]. Mycotoxin. Acyl-CoA-cholesterol acyltransferase (ACAT) inhibitor [3, 6]. Anticancer compound. Cytotoxic [4]. Non-peptidic oxytocin receptor antagonist [5]. Calpain inhibitor [7].
Purity:
>95% (HPLC)
Signal word:
Warning
SMILES:
COC1=C(C=CC2=C1C(=O)OCC1=C(O2)C(O)=CC(C)=C1)C(O)CC(C)C
Solubility Chemicals:
Soluble in DMSO, ethanol or methanol.
Source / Host:
Isolated from Penicillium sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 3 years after receipt when stored at -20°C.
References
Structure of penicillide, a new metabolite produced by a Penicillium sp.: T. Sassa, et al.; Tetrahedron Lett. 15, 3941 (1974) | Penicillide and dehydroisopenicillide from Talaromyces derxii: K. Suzuki, et al.; Phytochemistry 30, 2096 (1991) | Purpactins, new inhibitors of acyl-CoA:cholesterol acyltransferase produced by Penicillium purpurogenum. III. Chemical modification of purpactin A: H. Nishida, et al.; J. Antibiot. (Tokyo) 44, 152 (1991) | Vermixocins A and B, two novel metabolites from Penicillium vermiculatum: B. Proksa, et al.; J. Antibiot. (Tokyo) 45, 1268 (1992) | Potent, non-peptidic oxytocin receptor antagonists from a natural source: G.M. Salituro, et al.; Bioorg. Med. Chem. Lett. 3, 337 (1993) | AS-186 compounds, new inhibitors of acyl-CoA: cholesterol acyltransferase from Penicillium asperosporum KY1635: K. Kuroda, et al.; J. Antibiot. (Tokyo) 47, 16 (1994) | Penicillide, a Nonpeptide Calpain Inhibitor, Produced by Penicillium sp. F60760: M.C: Chung, et al.; J. Microbiol. Biotechnol. 8, 188 (1998)
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