Dihydromanumycin A
| Code | Size | Price |
|---|
| BVT-0414-M001 | 1 mg | £160.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Appearance:
Yellow powder.
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS07
Handling Advice:
Protect from light.
Hazards:
H302, H312, H319
InChi:
InChI=1S/C31H40N2O7/c1-5-6-11-19(2)16-20(3)17-21(4)30(38)32-22-18-31(39,29-28(40-29)27(22)37)15-10-8-7-9-12-25(36)33-26-23(34)13-14-24(26)35/h7-10,12,15-19,27-29,34,37,39H,5-6,11,13-14H2,1-4H3,(H,32,38)(H,33,36)/b8-7+,12-9+,15-10+,20-16+,21-17+/t19-,27+,28-,29-,31+/m1/s1
InChiKey:
OJRKFWPAASPEFZ-OOQJEELLSA-N
Long Description:
Chemical. Formula: C31H40N2O7. MW: 552.7. Derivative from Manumycin A. Derivative of the farnesyltransferase inhibitor Manumycin A (Prod. No. BVT-0091 http://www.adipogen.com/bvt-0091/manumycin-a.html ). This compound has not yet been thoroughly tested for its biological activity.
Molecular Formula:
C31H40N2O7
Molecular Weight:
552.7
Package Type:
Plastic Vial
Precautions:
P270, P280, P301, P312, P302, P352, P312
Product Description:
Derivative of the farnesyltransferase inhibitor Manumycin A (Prod. No. BVT-0091 http://www.adipogen.com/bvt-0091/manumycin-a.html ). This compound has not yet been thoroughly tested for its biological activity.
Purity:
>95% (TLC; NMR)
Signal Word:
Warning
SMILES:
CCCC[C@@H](C)C=C(/C)C=C(/C)C(=O)NC1=C[C@@](O)(C=CC=CC=CC(=O)NC2=C(O)CCC2=O)[C@@H]2O[C@@H]2[C@H]1O
Solubility Chemicals:
Soluble in DMSO or dichloromethane. Decomposable with acid. Instable against acids and bases.
Source / Host:
Derivative from Manumycin A.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
References
The structure of manumycin: A. Zeeck, et al.; J. Antibiot. 40, 1530 (1987) | Inhibitors of Rasfarnesyltransferases: F. Tamanoi; TIBS 18, 349 (1993) (Review) | Identification of Ras farnesyltransferase inhibitors by microbial screening: M. Hara, et al.; PNAS 90, 2281 (1993) | The manumycin-group metabolites: I. Sattler, et al.; Nat. Prod. Rep. 15, 221 (1998)