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AdipoGen Life Sciences

PARP-2 [ARTD2] (mouse) (rec.) (His) (high purity)

Product Code:
 
AG-40T-0012
Product Group:
 
Recombinant Proteins
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Shipping:
 
Dry Ice
Storage:
 
-20°C
 

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AG-40T-0012-C01010 ug£277.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
Poly(ADP-ribose) Polymerase; ADP-ribosyltransferase Diphtheria Toxin-like 2; NAD(+) ADP-ribosyltransferase 2
Biological Activity:
>600U/mg protein.
Concentration:
Lot dependent (0.2-1mg/ml)
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol.
Handling Advice:
After opening, prepare aliquots and store at -80°C.Avoid freeze/thaw cycles.
Long Description:
Protein. Mouse full-length PARP-2 [ARTD2] is fused to a His-tag. Source: Sf21 cells. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol. Purity: >98% (SDS-PAGE). PARP-2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
NCBI, Uniprot Number:
O88554
Package Type:
Plastic Vial
Product Description:
PARP-2 [ARTD2] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Purity:
>98% (SDS-PAGE)
Sequence:
Mouse full-length PARP-2 [ARTD2] is fused to a His-tag.
Source / Host:
Sf21 cells
TAGs:
His
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -80°C.

References

Identification of lysines 36 and 37 of PARP-2 as targets for acetylation and auto-ADP-ribosylation: S.S. Haenni, et al.; Int. J. Biochem. Cell Biol. 40, 2274 (2008)