Imperatorin

Imperatorin, a furanocoumarin from Angelica dahurica (Umbelliferae), induces cytochrome c-dependent apoptosis in human promyelocytic leukaemia, HL-60 Cells: H.O. Pae, et al.; Pharmacol. Toxicol. 91, 40 (2002) | Coumarins from Opopanax chironium. New dihydrofuranocoumarins and differential induction of apoptosis by imperatorin and heraclenin: G. Appendino, et al.; J. Nat. Prod. 67, 532 (2004) | Imperatorin inhibits HIV-1 replication through an Sp1-dependent pathway: R. Sancho, et al.; J. Biol. Chem. 279, 37349 (2004) | Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT: N. Marquez, et al.; Planta Med. 70, 1016 (2004) | Imperatorin induces vasodilatation possibly via inhibiting voltage dependent calcium channel and receptor-mediated Ca2+ influx and release: J. Y. He, et al.; Eur. J. Pharmacol. 573, 170 (2007) | Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts: C.H.Tang, et al.; Eur. J. Pharmacol. 579, 40 (2008) | Development of a fission yeast-based high-throughput screen to identify chemical regulators of cAMP phosphodiesterases: F.D. Ivey, et al.; J. Biomol. Screen. 13, 62 (2008) | Furanocoumarins-imperatorin inhibits myocardial hypertrophy both in vitro and in vivo: Y. Zhang, et al.; Fitoterapia 81, 1188 (2010) | Distinct effects of imperatorin on allergic rhinitis: imperatorin inhibits caspase-1 activity in vivo and in vitro: H.A. Oh, et al.; J. Pharmacol. Exp. Ther. 339, 72 (2011) | Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory activity of imperatorin from Glehnia littoralis: G.J. Huang, et al.; J. Agric. Food Chem. 60, 1673 (2012) | Anticancer effects of imperatorin isolated from Angelica dahurica: induction of apoptosis in HepG2 cells through both death-receptor- and mitochondria-mediated pathways: K.W. Luo, et al.; Chemotherapy 57, 449 (2011) | Imperatorin Attenuates LPS-Induced Inflammation by Suppressing NF-kappaB and MAPKs Activation in RAW 264.7 Macrophages: W. Guo, et al.; Inflammation 35, 1764 (2012) | Antilisterial potential of imperatorin and limonin from poncirus trifoliata rafin: A. Rahman, et al.; J. Food Biochem. 36, 217 (2012) | Structural Modeling and Identification of Imperatorin as Novel L-Type Calcium Channel Blocker: W. Lu, et al.; Med. Chem. 9, 993 (2013) | Imperatorin sensitizes anoikis and inhibits anchorage-independent growth of lung cancer cells: K. Choochuay, et al.; J. Nat. Med. 67, 599 (2013) | Imperatorin?pharmacological meaning and analytical clues: profound investigation: E. Koziol & K. Skalicka-Wozniak; Phytochem. Rev. 15, 627 (2016) | Imperatorin possesses notable anti?inflammatory activity in vitro and in vivo through inhibition of the NF?kappaB pathway: X. Zhang, et al.; Mol. Med. Rep. 16, 8619 (2017)