Fuscin
Product Code: AG-CN2-0138
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0138-M001 | 1 mg | £165.00 |
Quantity:
| AG-CN2-0138-MM25 | 2.5 mg | £360.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
3,4,7,9-Tetrahydroxy-6-methyl-1H-phenalen-1-one
Appearance:
Brown solid.
CAS:
83-85-2
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.
Hazards:
H302, H312, H332
InChi:
InChI=1S/C15H16O5/c1-7-11-9(6-10(16)19-7)8-4-5-15(2,3)20-14(8)13(18)12(11)17/h6-7,17H,4-5H2,1-3H3
InChiKey:
OSJKAGRXDVEZQO-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 83-85-2. Formula: C15H16O5. MW: 276.3. Isolated from Oidiodendron sp. Mycotoxin. Antibacterial agent. ADP transport inhibitor. Mitochondrial respiration and oxidative phosphorylation inhibitor. Human CCR5 receptor antagonist. Anti-HIV compound.
MDL:
MFCD00599032
Molecular Formula:
C15H16O5
Molecular Weight:
276.3
Package Type:
Vial
Precautions:
P261, P301, P312, P302, P352, P304, P340
Product Description:
Mycotoxin. Antibacterial agent. ADP transport inhibitor. NADH dehydrogenase (NADH-Coenzyme Q oxidoreductase; Complex I) inhibitor. Inhibits mitochondrial respiration and oxidative phosphorylation (OXPHOS). Human CCR5 receptor antagonist. Anti-HIV compound.
Purity:
>95% (HPLC)
Signal word:
Warning
SMILES:
CC1OC(=O)C=C2C3=C(OC(C)(C)CC3)C(=O)C(O)=C12
Solubility Chemicals:
Soluble in DMSO. Insoluble in water.
Source / Host:
Isolated from Oidiodendron sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Fuscin, an antibacterial pigment from Oidiodendron fuscum Robak: S.E. Michael; Biochem. J. 1948, 42 (1948) | Fuscin, an Inhibitor of NADH Dehydrogenase: P.M. Vignais; Inhibitors Tools in Cell Research 20, 274 (1969) | Fuscin, an inhibitor of respiration and oxidative phosphorylation in ox-neck muscle mitochondria: K.S. Cheah; Biochim. Biophys. Acta 275, 1 (1972) | Fuscin, an inhibitor of mitochondrial SH-dependent transport-linked functions: P.M. Vignais & P.V. Vignais; Biochim. Biophys. Acta 325, 357 (1973) | 10-Methoxydihydrofuscin, fuscinarin, and fuscin, novel antagonists of the human CCR5 receptor from Oidiodendron griseum: K. Yoganathan, et al.; J. Nat. Prod. 66, 1116 (2003)
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