Rubratoxin A
Product Code: AG-CN2-0092
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0092-C250 | 250 ug | £290.00 |
Quantity:
| AG-CN2-0092-C500 | 500 ug | £510.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Blue Ice
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
BRN 1633008; HSDB 3532
Appearance:
White powder.
CAS:
22467-31-8
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.
Hazards:
H302, H312, H319
InChi:
InChI=1S/C26H32O11/c1-2-3-4-5-7-15(27)20-18-13(23(31)36-25(18)33)10-12(21(29)16-8-6-9-17(28)35-16)11-14-19(22(20)30)26(34)37-24(14)32/h6,9,12,15-16,20-23,27,29-31H,2-5,7-8,10-11H2,1H3/t12-,15+,16-,20+,21-,22+,23?/m0/s1
InChiKey:
XOEFANNJIKAWGX-AWYIYDNTSA-N
Long Description:
Chemical. CAS: 22467-31-8. Formula: C26H32O11. MW: 520.2. Isolated from Penicillium sp. Mycotoxin. Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP. Antitumor agent. Antimetastatic.
MDL:
MFCD01735286
Molecular Formula:
C26H32O11
Molecular Weight:
520.2
Package Type:
Vial
Precautions:
P270, P280, P301, P312, P302, P352, P312
Product Description:
Mycotoxin [1]. Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP [2]. Antitumor agent. Antimetastatic [2].
Purity:
>95% (HPLC)
Signal word:
Warning
SMILES:
[H][C@]1(CC=CC(=O)O1)[C@@H](O)[C@@]1([H])CC2=C(C(=O)OC2O)[C@@]([H])([C@H](O)CCCCCC)[C@H](O)C2=C(C1)C(=O)OC2=O
Solubility Chemicals:
Soluble in DMSO or acetone. Methanol or ethanol are not recommended as solvents, as they esterify Rubratoxin A.
Source / Host:
Isolated from Penicillium sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 3 years after receipt when stored at -20°C.
References
The structure of rubratoxin A, a toxic metabolite of Penicillium rebrum: M.O. Moss, et al.; Tetrahedron Lett. 5, 367 (1969) | Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis: S. Wada, et al.; Cancer Sci. 101, 743 (2010)
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