Nocardamine
Product Code: AG-CN2-0150
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0150-M001 | 1 mg | £135.00 |
Quantity:
| AG-CN2-0150-M005 | 5 mg | £510.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Deferrioxamine E; Desferrioxamine E
Appearance:
White to off-white solid.
CAS:
26605-16-3
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C27H48N6O9/c34-22-10-14-26(38)32(41)20-8-3-6-18-30-24(36)12-15-27(39)33(42)21-9-2-5-17-29-23(35)11-13-25(37)31(40)19-7-1-4-16-28-22/h40-42H,1-21H2,(H,28,34)(H,29,35)(H,30,36)
InChiKey:
NHKCCADZVLTPPO-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 26605-16-3. Formula: C27H48N6O9. MW: 600.7. Isolated from Streptomyces sp. K04-0144. Antibiotic. Anti-mycobacterial. Siderophore (iron (Fe) chelating compound). Inducer of morphological changes in insect cells. Antioxidant. Anticancer compound.
MDL:
MFCD08457937
Molecular Formula:
C27H48N6O9
Molecular Weight:
600.7
Package Type:
Vial
Product Description:
Antibiotic [1, 6]. Anti-mycobacterial [7]. Siderophore (iron (Fe) chelating compound) [5, 8]. Inducer of morphological changes in insect cells [3]. Antioxidant [4]. Anticancer compound [2, 8].
Purity:
>95% (HPLC)
SMILES:
ON1CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC1=O
Solubility Chemicals:
Soluble in DMSO, methanol, ethanol or water.
Source / Host:
Isolated from Streptomyces sp. K04-0144.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
The description and antibiotic production of Streptomyces hygroscopicus var. geldanus: C. DeBoer & A. Dietz; J. Antibiot. 29, 1182 (1976) | Neuroblastoma sensitivity to growth inhibition by deferrioxamine: evidence for a block in G1 phase of the cell cycle: C. Brodie, et al.; Cancer Res. 53, 3968 (1993) | Morphological changes in insect BM-N4 cells induced by nocardamine: K. Matsubara, et al.; Biosci. Biotechnol. Biochem. 62, 2049 (1998) | Antioxidant properties of desferrioxamine E, a new hydroxamate antioxidant: E. Shimoni, et al.; J. Am. Oil Chem. Soc. 75, 1453 (1998) | A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases: G.L. Challis; ChemBioChem 6, 601 (2005) | Desferrioxamine E produced by Streptomyces griseus stimulates growth and development of Streptomyces tanashiensis: K. Yamanaka, et al.; Microbiology 151, 2899 (2005) | Cyclic peptides of the nocardamine class from a marine-derived bacterium of the genus Streptomyces: H.S. Lee, et al.; J. Nat. Prod. 68, 623 (2005) | Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activity: N.I. Kalinovskaya, et al.; Microbiol. Res. 166, 654 (2011)
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