Meglumine
Product Code: AG-CN2-0413
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0413-G001 | 1 g | £30.00 |
Quantity:
| AG-CN2-0413-G005 | 5 g | £60.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
N-Methyl-D-glucamine; NSC52907; NSC7391; 1-Deoxy-1-methylaminosorbitol
Appearance:
White to off-white crystalline powder.
CAS:
6284-40-8
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.
InChi:
InChI=1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3
InChiKey:
MBBZMMPHUWSWHV-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 6284-40-8. Formula: C7H17NO5. MW: 195.2. Synthetic. Amino sugar derived from sorbitol. Used as an excipient (an inert substance) in pharmaceuticals that improves solubility, drug release rate and stabilization of anionic drug substances. Counter ion used to replace sodium. It is impermeable towards cell membranes with comparable osmotic activity like sodium. Widely used in the preparation of contrast/radiopaque media in combination with iodine containing compounds, such as diatrizoate meglumine and iodipamide meglumine. Examples of meglumine-combined drugs are flunixin meglumine (used as a veterinary anti-inflammatory and analgesic) and meglumine antimoniate (antiprotozoal to treat leishmaniasis).
MDL:
MFCD00004707
Molecular Formula:
C7H17NO5
Molecular Weight:
195.2
Package Type:
Vial
Product Description:
Used as an excipient (an inert substance) in pharmaceuticals that improves solubility, drug release rate and stabilization of anionic drug substances. Counter ion used to replace sodium. It is impermeable towards cell membranes with comparable osmotic activity like sodium. Widely used in the preparation of contrast/radiopaque media in combination with iodine containing compounds, such as diatrizoate meglumine and iodipamide meglumine. Examples of meglumine-combined drugs are flunixin meglumine (used as a veterinary anti-inflammatory and analgesic) and meglumine antimoniate (antiprotozoal to treat leishmaniasis).
Purity:
>95% (NMR)
SMILES:
[H]C(O)(CO)C([H])(O)C([H])(O)C([H])(O)CNC
Solubility Chemicals:
Soluble in DMSO or water. Slightly soluble in ethanol.
Source / Host:
Synthetic. Amino sugar derived from sorbitol.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Ternary amorphous composites of celecoxib, poly(vinyl pyrrolidone) and meglumine with enhanced solubility: P. Gupta & A.K. Bansal; Pharmazie 60, 830 (2005) | Modeling of drug release from celecoxib-PVPmeglumine amorphous system: P. Gupta & A.K. Bansal; PDA. J. Pharm. Sci. Technol. 59, 346 (2005) | Molecular interactions in celecoxib-PVPmeglumine amorphous system: P. Gupta & A.K. Bansal; J. Pharm. Pharmacol. 57, 303 (2005) | Enhanced oral delivery of antimony from meglumine antimoniate/b-cyclodextrin nanoassemblies: F. Frezard, et al.; Int. J. Pharm. 347, 102 (2008) | Generation of formaldehyde by pharmaceutical excipients and its absorption by meglumine: M. Fujita, et al.; Chem. Pharm. Bull. 57, 1096 (2009) | Stabilization by meglumine of an amine compound degraded by formaldehyde in tablets: M. Fujita, et al.; Int. J. Pharm. 386, 195 (2010)