Butyrolactone II
Product Code: AG-CN2-0423
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0423-C500 | 500 ug | £120.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Appearance:
Brown amorphous solid.
CAS:
87414-44-6
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS07
Handling Advice:
Protect from light.Protect from moisture.
Hazards:
H302, H312, H332
InChi:
InChI=1S/C19H16O7/c1-25-18(24)19(10-11-2-6-13(20)7-3-11)15(16(22)17(23)26-19)12-4-8-14(21)9-5-12/h2-9,20-22H,10H2,1H3
InChiKey:
AEKPZNDJHWFONI-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 87414-44-6. Formula: C19H16O7. MW: 356.3. Isolated from Aspergillus sp. Antibiotic. Weak cytotoxic towards bacterial and cancer cell lines. 5-Lipoxygenase (5-LOX) inhibitor. Shows DPPH (2,2-diphenyl-1-picrylhydrazyl) radical-scavening activity.
MDL:
MFCD09752715
Molecular Formula:
C19H16O7
Molecular Weight:
356.3
Package Type:
Vial
Precautions:
P261, P301, P312, P302, P352, P304, P340
Product Description:
Antibiotic. Weak cytotoxic towards bacterial and cancer cell lines [1-3]. 5-Lipoxygenase (5-LOX) inhibitor [4, 5]. Shows DPPH (2,2-diphenyl-1-picrylhydrazyl) radical-scavening activity [5].
Purity:
>97% (HPLC)
Signal Word:
Warning
SMILES:
COC(=O)[C@]1(CC2=CC=C(O)C=C2)OC(=O)C(O)=C1C1=CC=C(O)C=C1
Solubility Chemicals:
Soluble in DMSO or ethanol.
Source / Host:
Isolated from Aspergillus sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
References
Metabolities of the Strain IFO 8835: N. Kiriyama, et al.; Chem. Pharm. Bull. 25, 2593 (1977) | Biosynthesis of butyrolactone derivatives isolated from strains IFO 8835 and 4100: K. Nitta, et al.; Chem. Pharm. Bull. 31, 1528 (1983) | Butyrolactones from Aspergillus terreus: K.V. Rao, et al.; Chem. Pharm. Bull. 48, 559 (2000) | Butyrolactones, inhibitors of 5-lipoxygenase from fungal metabolites: F.S. Wang, et al.; J. Chin. Pharm. Sci. 19, 251 (2010) | Soybean lipoxygenase inhibitory and DPPH radical-scavenging activities of aspernolide A and butyrolactones I and II: Y. Sugiyama, et al.; Biosci. Biotechnol. Biochem. 74, 881 (2010)