ABCC3 Antibody

ProSci
Product Code: PSI-25-881
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-25-881-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ABCC3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human MCF-7 at 0.2-1 ug/ml.
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Antibody used in WB on Hum. Adult Placenta at 1 ug/ml.

Antibody used in WB on Human MCF-7 at 0.2-1 ug/ml.
Antibody used in WB on Hum. Adult Placenta at 1 ug/ml.

Further Information

Additional Names:
ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2
Application Note:
ABCC3 antibody can be used for detection of ABCC3 by ELISA at 1:312500. ABCC3 antibody can be used for detection of ABCC3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
ABCC3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
  • Muller, P., (2008) Leuk. Res. 32 (6), 919-929.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ABCC3.
NCBI Gene ID #:
8714
NCBI Official Name:
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
NCBI Official Symbol:
ABCC3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
168 kDa
Protein Accession #:
NP_003777
Protein GI Number:
9955970
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,Cancer
Swissprot #:
O15438
User NOte:
Optimal dilutions for each application to be determined by the researcher.