Herbimycin A

Herbimycin, a new antibiotic produced by a strain of Streptomyces: S. Omura, et al.; J. Antibiot. (Tokyo) 32, 255 (1979) | A new activity of herbimycin A: inhibition of angiogenesis: T. Yamashita, et al.; J. Antibiot. (Tokyo) 42, 1015 (1989) | Effects of herbimycin A and various SH-reagents on p60v-src kinase activity in vitro: H. Fukazawa, et al; BBRC 173, 276 (1990) | Use and selectivity of herbimycin A as inhibitor of protein-tyrosine kinases: Y. Uehara & H. Fukazawa; Methods Enzymol. 201, 370 (1991) | Specific inhibition of cytoplasmic protein tyrosine kinases by herbimycin A in vitro: H. Fukazawa, et al.; Biochem. Pharmacol. 42, 1661 (1991) | Induction of differentiation of human leukemia cells with a structurally altered c-abl (bcr/abl) gene by herbimycin A, an inhibitor of tyrosine kinase activity: Y. Honma, et al.; Leukemia 6, 229 (1992) | Effect of herbimycin A, an inhibitor of tyrosine kinase, on protein tyrosine kinase activity and phosphotyrosyl proteins of Ph1-positive leukemia cells: M. Okabe, et al.; Leuk. Res. 18, 213 (1994) | Evidence for direct modification of NF kappa B by the tyrosine kinase inhibitor, herbimycin A: T.M. Mahon & L.A. O'Neill; Biochem. Soc. Trans. 23, 111S (1995) | Herbimycin A induces the 20 S proteasome- and ubiquitin-dependent degradation of receptor tyrosine kinases: L. Sepp-Lorenzino, et al.; J. Biol. Chem. 270, 16580 (1995) | Inhibition of PDGF-induced phospholipase D but not phospholipase C activation by herbimycin A: B.Y. Kim; BBRC 212, 1061 (1995) | Specific induction of the 70-kD heat stress proteins by the tyrosine kinase inhibitor herbimycin-A protects rat neonatal cardiomyocytes. A new pharmacological route to stress protein expression? S.D. Morris, et al.; J. Clin. Invest. 97, 706 (1996) | Inhibition of PDGF-induced phospholipase C activation by herbimycin A: B.Y. Kim, et al.; Biochim. Biophys. Acta 1311, 33 (1996) | Herbimycin A enhances apoptotic effect of chemotherapeutic drugs on K562 cells: H. Ren, et al.; Chin. Med. J. (Engl.) 111, 678 (1998) | Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs: M.V. Blagosklonny; Leukemia 16, 455 (2002) (Review) | Herbimycin A induces sympathetic neuron survival and protects against hypoxia: M.C. Cabral-da-Silva, et al.; Neuroreport 14, 2397 (2003) | Natural product origins of Hsp90 inhibitors: Y. Uehara; Curr. Cancer Drug Targets 3, 325 (2003) | Herbimycin A abrogates nuclear factor-kappaB activation by interacting preferentially with the IkappaB kinase beta subunit: S. Ogino, et al.; Mol. Pharmacol. 65, 1344 (2004) | c-Src is required for complex formation between the hepatitis C virus-encoded proteins NS5A and NS5B: a prerequisite for replication: A. Pfannkuche, et al.; Hepatology 53, 1127 (2011) | Inhibitors of tyrosine kinases and phosphatases as a tool for the investigation of microtubule role in plant cold response: Y.A. Sheremet, et al.; Tsitol Genet. 46, 3 (2012) | Transcriptome analyses of inhibitor-treated schistosome females provide evidence for cooperating Src-kinase and TGFbeta receptor pathways controlling mitosis and eggshell formation: C. Buro, et al.; PLoS Pathog. 9, e1003448 (2013)