Piperafizine B
| Code | Size | Price |
|---|
| BVT-0446-C500 | 500 ug | £130.00 |
Quantity:
| BVT-0446-M001 | 1 mg | £205.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
+4°C
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
3,6-Dibenzylidene-2,5-piperazinedione; 3,6-Dibenzylidene-2,5-dioxopiperazine; 3,6-Bis(phenylmethylene)-2,5-piperazinedione
Appearance:
Light yellow solid.
CAS:
74720-33-5
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light when in solution.
Hazards:
H302, H319
InChi:
InChI=1S/C18H14N2O2/c21-17-15(11-13-7-3-1-4-8-13)19-18(22)16(20-17)12-14-9-5-2-6-10-14/h1-12H,(H,19,22)(H,20,21)/b15-11-,16-12+
InChiKey:
RFSUEJIDSYCCLL-UKVBVZPVSA-N
Long Description:
Chemical. CAS: 74720-33-5. Formula: C18H14N2O2. MW: 290.3. Isolated from Streptomyces thioluteus. Diketopiperazine derivative. Analog of Piperafizine A. Potentiator of vincristine cytotoxicity.
MDL:
MFCD00504361
Molecular Formula:
C18H14N2O2
Molecular Weight:
290.3
Package Type:
Plastic Vial
Precautions:
P270, P280, P301, P312, P305, P351, P338
Product Description:
Diketopiperazine derivative. Analog of Piperafizine A. Potentiator of vincristine cytotoxicity.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
O=C1NC(=C/C2=CC=CC=C2)C(=O)NC1=CC1=CC=CC=C1
Solubility Chemicals:
Soluble in DMSO.
Source / Host:
Isolated from Streptomyces thioluteus.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at +4°C.
References
The production of 3-benzylidene-6-isobutylidene-2,5-dioxopiperazine, 3,6-dibenzylidene-2,5-dioxopiperazine,3-benzyl-6-benzylidene-2,5-dioxopiperazine, and 3,6-dibenzyl-2,5-dioxopiperazine by a variant of Streptomyces noursei: R. Brown, et al.; J. Org. Chem. 30, 277 (1960) | alpha,beta-unsaturated carboxylic acid derivatives. Part 18. Syntheses of geometric isomers of 3,6-dibenzylidene and 3-p-anisylidene-6-benzylidene-2,5-piperazinedions: C. Shin, et al.; J. Chem. Soc. Perkin Trans. 1, 419 (1980) | Molecular and electronic structure of the dehydroalanine derivatives: the cyclicdipeptide of dehydrophenylalanine: D. Ajo, et al.; Tetrahedron 41, 5543 (1985) | Piperafizines A and B, potentiators of cytotoxicity of vincristine: H. Kamei, et al.; J. Antibiot. 43, 1018 (1990)
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