Z-Leu-Leu-Phe-CHO
| Code | Size | Price |
|---|
| AG-CP3-0021-M001 | 1 mg | £65.00 |
Quantity:
| AG-CP3-0021-M005 | 5 mg | £175.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C
Further Information
Alternate Names/Synonyms:
Z-LLF-CHO; Proteasome Inhibitor II
Appearance:
Solid lyophilized powder.
CAS:
133429-58-0
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Avoid freeze/thaw cycles.
InChi:
InChI=1S/C29H39N3O5/c1-20(2)15-25(27(34)30-24(18-33)17-22-11-7-5-8-12-22)31-28(35)26(16-21(3)4)32-29(36)37-19-23-13-9-6-10-14-23/h5-14,18,20-21,24-26H,15-17,19H2,1-4H3,(H,30,34)(H,31,35)(H,32,36)/t24-,25-,26-/m1/s1
InChiKey:
LIOIGKLWXFXXEG-TWJOJJKGSA-N
Long Description:
Chemical. CAS: 133429-58-0. Formula: C29H39N3O5. MW: 509.7. Reversible and cell permeable proteasome inhibitor. Specifically inhibits the chymotrypsin-like activity of the proteasome. Calpain and cathepsin inhibitor. Does not inhibit the peptidyl-glutamyl peptide hydrolyzing activity of MPC.
MDL:
MFCD01862616
Molecular Formula:
C29H39N3O5
Molecular Weight:
509.7
Package Type:
Vial
Product Description:
Reversible and cell permeable proteasome inhibitor. Specifically inhibits the chymotrypsin-like activity of the proteasome. Calpain and cathepsin inhibitor. Does not inhibit the peptidyl-glutamyl peptide hydrolyzing activity of MPC.
Purity:
>95% (HPLC)
Sequence:
Z-Leu-Leu-Phe-aldehyde
SMILES:
CC(C)C[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C=O
Solubility Chemicals:
Soluble in DMSO.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.
References
Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex: A. Vinitsky, et al.; Biochemistry 31, 9421 (1992) | Tumor necrosis factor-related apoptosis inducing ligand expression and activity in hen granulosa cells: A.L. Johnson, et al.; Reproduction 133, 609 (2007) | Profiling drug-induced cell death pathways in the zebrafish lateral line: A.B. Coffin, et al.; Apoptosis 18, 393 (2013)
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