Aerothionin
Product Code: AG-CN2-0453
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0453-M001 | 1 mg | £115.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
NSC177380
Appearance:
Colorless to white adhered film.
CAS:
28714-26-3
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light.Protect from moisture.
InChi:
InChI=1S/C24H26Br4N4O8/c1-37-17-11(25)7-23(19(33)15(17)27)9-13(31-39-23)21(35)29-5-3-4-6-30-22(36)14-10-24(40-32-14)8-12(26)18(38-2)16(28)20(24)34/h7-8,19-20,33-34H,3-6,9-10H2,1-2H3,(H,29,35)(H,30,36)/t19-,20-,23+,24+/m0/s1
InChiKey:
BJWQSQOWGBUSFC-UWXQAFAOSA-N
Long Description:
Chemical. CAS: 28714-26-3. Formula: C24H26Br4N4O8. MW: 818.1. Isolated from Suberea sp. Antibiotic. Anti-mycobacterial.
MDL:
MFCD14635399
Molecular Formula:
C24H26Br4N4O8
Molecular Weight:
818.1
Package Type:
Vial
Product Description:
Antibiotic. Anti-mycobacterial.
Purity:
>98% (HPLC)
SMILES:
COC1=C(Br)[C@H](O)[C@]2(CC(=NO2)C(=O)NCCCCNC(=O)C2=NO[C@@]3(C2)C=C(Br)C(OC)=C(Br)[C@@H]3O)C=C1Br
Solubility Chemicals:
Soluble in DMSO or 100% ethanol.
Source / Host:
Isolated from Suberea sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
References
Aerothionin, a tetrabromo-compound from Aplysina aerophoba and Verongia thiona: E. Fattorusso, et al.; J. Chem. Soc. D: Chem. Commun. 12, 752 (1970) | Aerothionin and homoaerothionin: Two tetra bromo spirocyclohexadienylisoxazoles from Verongia sponges: K. Moody, et al.; J. C. S. Perkin Trans. I, 18 (1972) | An x-ray study of aerothionin from Aplysina fistularis: J.A. McMillan, et al.; Tetrahedron Lett. 22, 39 (1981). | Chemistry of sponges, VII. 11,19-Dideoxyfistularin 3 and 11-Hydroxyaerothionin, bromotyrosine derivatives from Pseudoceratina durissima: M.R. Kernan & R.C. Cambie; J. Nat. Prod. 53, 615 (1990) | Chemistry of Verongida sponges, II. Constituents of the Caribbean sponge Aplysina fistularis forma fulva: P. Ciminiello, et al.; J. Nat. Prod. 57, 705 (1994) | Aerothionin, a bromotyrosine derivative with antimycobacterial activity from the marine sponge Aplysina gerardogreeni (Demospongia): R. Encarnacion-Dimayuga, et al.; Pharm. Biol. 41, 384 (2003) | Asymmetric synthesis of aerothionin, a marine dimeric spiroisoxazoline natural product, employing optically active spiroisoxazoline derivative: T. Ogamino, et al.; Tetradedron Lett. 47, 727 (2006) | Bioactive constituents from the marine crinoid Himerometra magnipinna: N. Shao, et al.; J. Nat. Prod. 70, 869 (2007) | Bioactive brominated metabolites from the Red Sea sponge Suberea mollis: M.I. Abou-Shoer, et al.; J. Nat. Prod. 71, 1464 (2008)