Myostatin Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-199-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-199-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized Myostatin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Myostatin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protei
Documents
Further Information
Additional Names:
GDF8, MSLHP, GDF8, Myostatin, GDF-8
Background:
Myostatin is a TGF-beta family member that acts as an inhibitor of skeletal muscle growth. This muscle-specific cytokine interacts with Activin type I and type II receptors, and suppresses myoblast proliferation by arresting cell-cycle in the G1 phase. Suppression of myostatin activity facilitates muscle formation and may be useful in reducing and/or preventing adiposity and type-2 diabetes. Myostatin activity can be blocked by the Activin-binding protein Follistatin, and by the propeptide of Myostatin. Recombinant Human myostatin is a 25.0 kDa protein consisting of two identical 109 amino acid polypeptides linked by a single disulfide bond.
Biological Activity:
Biological activity was determined by its ability to inhibit the proliferation of MPC - 11 cells. The expected ED50 for this effect is 17.0 - 25.0 ng/mL.
NCBI Gene ID #:
2660
NCBI Official Name:
myostatin
NCBI Official Symbol:
MSTN
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_005250.1
Protein GI Number:
4885259
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
O14793