Soluble TRAIL Receptor-2 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-310-0.01mg | 0.01mg | £300.00 |
Quantity:
| PSI-40-310-0.05mg | 0.05mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized Soluble TRAIL Receptor-2 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Soluble TRAIL Receptor-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at
Documents
Further Information
Additional Names:
DR5, CD262, KILLER, TRICK2, TRICKB, ZTNFR9, TRAILR2, TRICK2A, TRICK2B, TRAIL-R2, KILLER/DR5, DR5, UNQ160/PRO186, Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, TRAIL receptor 2
Background:
TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain", which can activate the cell's apoptotic machinery. These receptors are activated by binding to either membrane anchored or soluble TRAIL/Apo2L. Recombinant human soluble TRAIL Receptor-2/DR5 is a 14.9 kDa protein (133 amino acid residues) consisting of the TNFR homologous, cysteine rich portion of the extracellular domain.
Biological Activity:
Determined by its ability to inhibit apoptosis induced by Human sTRAIL/Apo2L in LN-18 cells (human glioblastoma cells).
NCBI Gene ID #:
8795
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 10b
NCBI Official Symbol:
TNFRSF10B
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_003833.4
Protein GI Number:
224494019
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
O14763