FGF acidic Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-493-0.01mg | 0.01mg | £300.00 |
Quantity:
| PSI-40-493-0.05mg | 0.05mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
The lyophilized FGF acidic recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted FGF acidic is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any prot
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Further Information
Additional Names:
Fam, Fgfa, Dffrx, Fgf-1, Fibroblast growth factor 1, Acidic fibroblast growth factor, FGF-1
Background:
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant murine FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.
Biological Activity:
Assay 1: The ED50 was determined by the dose - dependent stimulation of thymidine uptake by 3T3 cells in the presence of heparin is ≤ 0.5 ng/mL corresponding to a specific activity of ≥ 2 x 106 units/mg.
Assay 2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.2 ng/mL in the presence of 10 μg/mL heparin, corresponding to a specific activity of ≥ 5 x 106 units/mg.
Assay 2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.2 ng/mL in the presence of 10 μg/mL heparin, corresponding to a specific activity of ≥ 5 x 106 units/mg.
NCBI Gene ID #:
14164
NCBI Official Name:
fibroblast growth factor 1
NCBI Official Symbol:
Fgf1
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_034327.1
Protein GI Number:
6753850
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P61148