IFN gamma Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-449-0.02mg | 0.02mg | £300.00 |
Quantity:
| PSI-40-449-0.1mg | 0.1mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
The lyophilized IFN gamma recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IFN gamma is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protei
Documents
Further Information
Additional Names:
interferon gamma
Background:
IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-gamma is a 15.6 kDa protein containing 134 amino acid residues.
Biological Activity:
The ED50 was determined by a cytopathic affect inhibition assay with murine NIH 3T3 cells challenged with VSV virus was 0.1 ng/mL, corresponding to a specific activity of 1 x 107 units/mg.
NCBI Gene ID #:
15978
NCBI Official Name:
interferon gamma
NCBI Official Symbol:
Ifng
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
P01580
Protein GI Number:
23200041
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P01580