IL-3 beta Recombinant Protein
Code | Size | Price |
---|
PSI-40-463-0.005mg | 0.005mg | £300.00 |
Quantity:
PSI-40-463-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Rat
Storage:
The lyophilized IL-3 beta recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-3 beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protei
Documents
Further Information
Additional Names:
Csf2rb1
Background:
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant rat IL-3beta is a 16.3 kDa globular protein containing 144 amino acid residues.
Biological Activity:
The ED50 was determined by the dose - dependent stimulation of the proliferation of thymidine uptake by murine MC - 9 cells is < 10 ng/mL, corresponding to a specific activity of >1.0 x 105 units/mg.
NCBI Gene ID #:
171081
NCBI Official Name:
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
NCBI Official Symbol:
Csf2rb
NCBI Organism:
Rattus norvegicus
Physical State:
Lyophilized
Protein Accession #:
NP_598239.1
Protein GI Number:
19424232
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q78ZF5