TNFRSF 18 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-354-0.1mg | 0.1mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
AITR, GITR, TNFRSF18, CD357
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Background References:
- Gurney A.L., et al., 1999, Curr. Biol. 9:215-218.
- Park MS., et al., 2007, Yonsei Med J 48 (5): 839-46.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human GITR, His Tag (Cat# 96-354) at 2 ug/mL (100 ul/well) can bind Human GITR Ligand, Fc Tag (Cat# GIL-H526a) with a linear range of 0.8-25 ng/mL.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
8784
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 18
NCBI Official Symbol:
TNFRSF18
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
16.4 kDa
Protein Accession #:
Q9Y5U5-1
Purity:
>92% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9Y5U5