Luteoreticulin
| Code | Size | Price |
|---|
| BVT-0457-C500 | 500 ug | £160.00 |
Quantity:
| BVT-0457-M001 | 1 mg | £280.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: n/a
Antibody Clone: n/a
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
Griseulin; 6-[1,3-Dimethyl-4-(4-nitrophenyl)-1,3-butadienyl]-4-methoxy-3-methyl-2H-pyran-2-one
Appearance:
Yellow solid.
CAS:
22388-89-2
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light when in solution.
InChi:
InChI=1S/C19H19NO5/c1-12(10-15-5-7-16(8-6-15)20(22)23)9-13(2)17-11-18(24-4)14(3)19(21)25-17/h5-11H,1-4H3/b12-10+,13-9+
InChiKey:
INCHGEJHIFBBOR-DSEBWEOJSA-N
Long Description:
Chemical. CAS: 22388-89-2. Formula: C19H19NO5. MW: 341.4. Isolated from Streptomyces thioluteus. Nitrophenyl pyranone derivative related to aureothin (Prod. No. BVT-0303 http://www.adipogen.com/bvt-0303/aureothin.html ). Insecticidal and nematocidal compound. Metabolites within this product class show pronounced antitumor and immunosuppressive activity.
MDL:
MFCD14635388
Molecular Formula:
C19H19NO5
Molecular Weight:
341.4
Package Type:
Plastic Vial
Product Description:
Nitrophenyl pyranone derivative related to aureothin (Prod. No. BVT-0303 http://www.adipogen.com/bvt-0303/aureothin.html ). Insecticidal and nematocidal compound. Metabolites within this product class show pronounced antitumor and immunosuppressive activity.
Purity:
>98% (NMR, HPLC)
SMILES:
COC1=C(C)C(=O)OC(=C1)C(C)=CC(C)=CC1=CC=C(C=C1)[N+]([O-])=O
Solubility Chemicals:
Soluble in DMSO, acetone or chloroform.
Source / Host:
Isolated from Streptomyces thioluteus.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at +4°C.
References
Structure of luteoreticulin, a nitro-containing metabolite of Streptomyces luteoreticuli: Y. Koyama, et al.; Tetrahedron Lett. 1969, 355 (1969) | Fermentative manufacture of pyrone insecticides: M. G. Nair; PCT Int. Appl. WO 9312656 A1 19930708 (1993) | Griseulin, a new nitro-containing bioactive metabolite produced by Streptomyces spp: M.G.Nair, et al.; J. Antibiot. (Tokyo) 46, 1762 (1993) | Structural revision of griseulin, a bioactive pyrone possessing a nitrophenyl unit: Y. Ishibashi, et al.; Chem. Lett. 23, 1747 (1994) | Convergent syntheses of luteoreticulin and didemethylluteoreticulin: J. W. Lyga; J. Heterocyclic Chem. 32, 515 (1995) | Rational design of modular polyketide synthases: Morphing the aureothin pathway into a luteoreticulin assembly line: Y. Sugimoto, et al.; Angew. Chem. Int. Edit. 53, 1560 (2014)
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