FGF-2 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-331-10ug | 10ug | £373.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
Basic Fibroblast Growth Factor, bFGF, Heparin Binding Growth Factor-2, HBGF-2
Application Note:
This recombinant proteins is for research use only.
Background:
FGF-2 (Basic fibroblast growth factor) belongs to the FGF superfamily that is made up of 22 different fibroblast growth factor genes. FGF-2 and FGF-1 (acidic FGF) are unique in that they do not follow the conventional signal sequence for secretion. FGF-2 is found in five isoforms via alternative initiation of translation. Signaling of FGF-2 occurs through the high-affinity tyrosine kinase receptors FGFR1-4. FGF-2 is a potent wide-spectrum mitogen whose overexpression is associated with immortalization and unregulated cell proliferation in many tumors. FGF-2 functions in angiogenesis, cell survival, tissue repair, embryonic development and inflammation. FGF-2 is widely used to maintain the self-renewal of human embryonic stem cells (ESCs) and to induce pluripotent stem cells. FGF-2 is an established neurogenic factor for proliferation and differentiation of multipotent neural stem cells both during development and in the adult mouse brain as well.
Buffer:
Contains PBS + 0.1mM DTT. Reconstitute with 100 μl sterile water.
Concentration:
0.1mg/ml after reconstitution.
Fusion Tag:
Tag Free
NCBI Gene ID #:
2247
NCBI Official Name:
fibroblast growth factor 2 (basic)
NCBI Official Symbol:
FGF2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
P09038
Protein GI Number:
261260095
Purity:
>95% (SDS-PAGE).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P12643