Dectin-1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-318-50ug | 50ug | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
C-type Lectin Domain Family 7 Member A, Beta-Glucan Receptor, Dendritic Cell-associated C-type Lectin 1, C-type Lectin Superfamily Member 12, DC-associated C-type Lectin 1
Application Note:
This recombinant proteins is for research use only.
Background:
Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.
Buffer:
Contains PBS. Reconstitute with 50 μl sterile water.
Concentration:
1mg/ml after reconstitution.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
56644
NCBI Official Name:
C-type lectin domain family 7, member a
NCBI Official Symbol:
Clec7a
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
Q6QLQ4
Protein GI Number:
408360305
Purity:
>95% (SDS-PAGE).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P19838