Fridamycin B
| Code | Size | Price |
|---|
| BVT-0470-M001 | 1 mg | £105.00 |
Quantity:
| BVT-0470-M005 | 5 mg | £300.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
Short Term: +4°C Long Term: +4°C
Documents
Further Information
Alternate Names/Synonyms:
3'-Epimer of Fridamycin A
Appearance:
Yellow to brown solid.
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light.
InChi:
InChI=1S/C25H26O10/c1-10-20(29)15(26)7-16(35-10)12-5-6-14-19(22(12)31)24(33)13-4-3-11(21(30)18(13)23(14)32)8-25(2,34)9-17(27)28/h3-6,10,15-16,20,26,29-31,34H,7-9H2,1-2H3,(H,27,28)/t10-,15+,16-,20-,25-/m1/s1
InChiKey:
LKLNNJGYAYDANM-XLTBZDRQSA-N
Long Description:
Chemical. Formula: C25H26O10. MW: 486.5. Isolated from Streptomyces parvulus. C-glycosidic angucyclinone derivative. Antibiotic. Antitumor agent. Antibacterial agent. Isomer of fridamycin A (Prod. No. BVT-0469).
Molecular Formula:
C25H26O10
Molecular Weight:
486.5
Package Type:
Plastic Vial
Product Description:
C-glycosidic angucyclinone derivative. Antibiotic. Antitumor agent. Antibacterial agent. Isomer of fridamycin A (Prod. No. BVT-0469).
Purity:
>98% (HPLC, NMR)
SMILES:
[H][C@@]1(C[C@H](O)[C@H](O)[C@@H](C)O1)C1=C(O)C2=C(C=C1)C(=O)C1=C(C=CC(C[C@@](C)(O)CC(O)=O)=C1O)C2=O
Solubility Chemicals:
Soluble in DMSO. Sparingly soluble in methanol or acetone.
Source / Host:
Isolated from Streptomyces parvulus.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. Store solutions at -20°C in the dark.
References
The structure of vineomycin B2: N. Imamura, et al.; J. Antibiot. 34, 1517 (1981) | Fridamycine, Anthracyclin-analoge Antibiotica: P. Knicke; Ph. D. Thesis Univ. Goettingen (1984) | Angucycline group antibiotics: J. Rohr & R. Thiericke; Nat. Prod. Rep. 9, 103 (1992) | Synthetic anthracyclines from anthraquinones: R. Cambie, et al.; Austr. J. Chem. 45, 483 (1992) | C-Aryl glycosides via tandem intramolecular benzyne-furan cycloadditions. Total synthesis of vineomycine B2 methyl ester: C.-L. Chen, et al.; JACS 128, 13696 (2006) | Convergent de novo synthesis of vineomycinione B2 methyl ester: Q. Chen, et al.; Chem. Comm. 49, 6806 (2013) | Total Synthesis of vineomycin B2: S. Kusumi, et al.; JACS 135, 15909 (2013) | Angucycline antibiotics and its derivatives from marine-derived actinomycete streptomyces sp. A6H: Z. Hu, et al.; Nat. Prod. Res. 30, 2551 (2016)