Procyanidin A2
Product Code: AG-CN2-0486
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0486-M001 | 1 mg | £60.00 |
Quantity:
| AG-CN2-0486-M005 | 5 mg | £160.00 |
Quantity:
| AG-CN2-0486-M025 | 25 mg | £490.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Storage:
Short Term: 4°C Long Term: -20°C
Documents
Further Information
Alternate Names/Synonyms:
(+)-Epicatechin-(4beta-8,2beta-O-7)-epicatechin; PCA2; Proanthocyanidin A2; PA2; Procyanidol A2; Procyanidin dimer A2
Appearance:
Pale pink solid.
CAS:
41743-41-3
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light.Protect from moisture and oxygen.
InChi:
InChI=1S/C30H24O12/c31-13-7-20(37)24-22(8-13)41-30(12-2-4-16(33)19(36)6-12)29(39)26(24)25-23(42-30)10-17(34)14-9-21(38)27(40-28(14)25)11-1-3-15(32)18(35)5-11/h1-8,10,21,26-27,29,31-39H,9H2/t21-,26-,27-,29-,30+/m1/s1
InChiKey:
NSEWTSAADLNHNH-LSBOWGMISA-N
Long Description:
Chemical. CAS: 41743-41-3. Formula: C30H24O12. MW: 576.5. Isolated from grape seeds (Vitis vinifera L). A-Type proanthocyanidine. Potent antioxidant. Free radical scavenger and lipid peroxidation inhibitor. Potent low-density lipoprotein (LDL) oxidation inhibitor. Antidiabetic. Prevents islet cell apoptosis, hyperglycemia and type 2 diabetes through it's antioxidant properties. Antibacterial agent. Antiviral. Shown to inhibit viral replication of canine distemper virus (CDV). Glycosyltransferase B (GTFB) inhibitor.
MDL:
MFCD10566019
Molecular Formula:
C30H24O12
Molecular Weight:
576.5
Package Type:
Vial
Product Description:
A-Type proanthocyanidine. Potent antioxidant. Free radical scavenger and lipid peroxidation inhibitor. Potent low-density lipoprotein (LDL) oxidation inhibitor. Antidiabetic. Prevents islet cell apoptosis, hyperglycemia and type 2 diabetes through it's antioxidant properties. Antibacterial agent. Antiviral. Shown to inhibit viral replication of canine distemper virus (CDV). Glycosyltransferase B (GTFB) inhibitor.
Purity:
>95% (NMR)
SMILES:
OC1=CC(O)=C([C@H](C2=C(O[C@H](C3=CC(O)=C(O)C=C3)[C@H](O)C4)C4=C(O)C=C2O5)[C@@H](O)[C@@]5(C6=CC(O)=C(O)C=C6)O7)C7=C1
Solubility Chemicals:
Soluble in DMSO, 100% ethanol or methanol. Sparingly soluble in water (0.1 mg/ml).
Source / Host:
Isolated from grape seeds (Vitis vinifera L).
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352211
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Phenolic constituents in the fruits of Cinnamomum zeylanicum and their antioxidant activity: G.K. Jayaprakasha, et al.; J. Agric. Food Chem. 54, 1672 (2006) | Influence of cranberry phenolics on glucan synthesis by glucosyltransferases and Streptococcus mutans acidogenicity: S. Gregoire, et al.; J. Appl. Microbiol. 103, 1960 (2007) | Influence of cranberry proanthocyanidins on formation of biofilms by Streptococcus mutans on saliva-coated apatitic surface and on dental caries development in vivo: H. Koo, et al.; Caries Res. 44, 116 (2010) | Doubly linked, A-type proanthocyanidin trimer and other constituents of Ixora coccinea leaves and their antioxidant and antibacterial properties: T.O. Idowu, et al.; Phytochemistry 71, 2092 (2010) | Inhibition of viral RNA synthesis in canine distemper virus infection by proanthocyanidin A2: L. Gallina, et al.; Antiviral Res. 92, 447 (2011) | Flavonoids from Lindera glauca blume as low-density lipoprotein oxidation inhibitors: G.W. Huh, et al.; Nat. Prod. Res. 28, 831 (2014) | Procyanidins from the stem wood of Machilus japonica and their inhibitory effect on LDL oxidation: H.J. Park, et al.; Arch. Pharm. Res. 37, 1403 (2014) | Chemical composition, antioxidant and antinociceptive properties of Litchi chinensis leaves: R.C. Castellain, et al.; J. Pharm. Pharmacol. 66, 1796 (2014) | Preventive effects of procyanidin A2 on glucose homeostasis, pancreatic and duodenal homebox 1, and glucose transporter 2 gene expression disturbance induced by bisphenol A in male mice: A. Ahangarpour, et al.; J. Physiol. Pharmacol. 67, 243 (2016)