LDK378
| Code | Size | Price |
|---|
| SYN-1199-M100 | 100 mg | Enquire |
Quantity:
| SYN-1199-M001 | 1 mg | £80.00 |
Quantity:
| SYN-1199-M005 | 5 mg | £115.00 |
Quantity:
| SYN-1199-M010 | 10 mg | £151.00 |
Quantity:
| SYN-1199-M050 | 50 mg | £467.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
LDK-378
Appearance:
Solid.
CAS:
1032900-25-6
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C28H36ClN5O3S/c1-17(2)37-25-15-21(20-10-12-30-13-11-20)19(5)14-24(25)33-28-31-16-22(29)27(34-28)32-23-8-6-7-9-26(23)38(35,36)18(3)4/h6-9,14-18,20,30H,10-13H2,1-5H3,(H2,31,32,33,34)
InChiKey:
VERWOWGGCGHDQE-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1032900-25-6. Formula: C28H36ClN5O3S. MW: 558.1. LDK378 is potent inhibitor against ALK with IC(50) of 0.2nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.
Molecular Formula:
C28H36ClN5O3S
Molecular Weight:
558.1
Package Type:
Plastic Vial
Product Description:
LDK378 is potent inhibitor against ALK with IC(50) of 0.2nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO (heat) or ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Targeting Anaplastic Lymphoma Kinase in Lung Cancer: A.T. Shaw & B. Solomon; Clin. Cancer Res. 17, 2081 (2011)
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