TAK-632
| Code | Size | Price |
|---|
| SYN-1203-M100 | 100 mg | Enquire |
Quantity:
| SYN-1203-M001 | 1 mg | £92.00 |
Quantity:
| SYN-1203-M005 | 5 mg | £151.00 |
Quantity:
| SYN-1203-M010 | 10 mg | £209.00 |
Quantity:
| SYN-1203-M050 | 50 mg | £771.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
TAK632
Appearance:
Solid.
CAS:
1228591-30-7
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C27H18F4N4O3S/c28-19-7-6-17(12-21(19)33-23(36)11-14-2-1-3-16(10-14)27(29,30)31)38-22-9-8-20-24(18(22)13-32)39-26(34-20)35-25(37)15-4-5-15/h1-3,6-10,12,15H,4-5,11H2,(H,33,36)(H,34,35,37)
InChiKey:
OJFKUJDRGJSAQB-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1228591-30-7. Formula: C27H18F4N4O3S. MW: 554.5. TAK-632 is a potent pan-RAF inhibitor with favorable in vitro activity (BRAF(V600E) IC(50) of 2.4nM.
Molecular Formula:
C27H18F4N4O3S
Molecular Weight:
554.5
Package Type:
Plastic Vial
Product Description:
TAK-632 is a potent pan-RAF inhibitor with favorable in vitro activity (BRAF(V600E) IC(50) of 2.4nM.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO or ethanol. Slightly soluble (<1mg/ml) in water.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Antitumor activity of the selective pan-RAF inhibitor TAK-632 in BRAF inhibitor-resistant melanoma: A. Nakamura, et al.; Cancer Res. 73, 7043 (2013)