GDC-0941
Code | Size | Price |
---|
SYN-1041-M100 | 100 mg | Enquire |
Quantity:
SYN-1041-M001 | 1 mg | £104.00 |
Quantity:
SYN-1041-M005 | 5 mg | £145.00 |
Quantity:
SYN-1041-M010 | 10 mg | £209.00 |
Quantity:
SYN-1041-M050 | 50 mg | £443.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Images
Documents
Further Information
Alternate Names/Synonyms:
GDC0941
Appearance:
Solid.
CAS:
957054-30-7
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H303, H317, H333
InChi:
InChI=1S/C23H27N7O3S2/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4,13-14H,5-12,15H2,1H3,(H,24,27)
InChiKey:
LHNIIDJUOCFXAP-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 957054-30-7. Formula: C23H27N7O3S2. MW: 513.6. GDC-0941 is a potent class I PI3 kinase (PI3K) inhibitor. It selectively binds to PI3K isoforms in an ATP-competitive manner. It has an IC(50) of 3nM, and shows slight selectivity toward p110beta (11-fold) and p110gamma (25-fold).
Molecular Formula:
C23H27N7O3S2
Molecular Weight:
513.6
Package Type:
Plastic Vial
Precautions:
P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
Product Description:
GDC-0941 is a potent class I PI3 kinase (PI3K) inhibitor. It selectively binds to PI3K isoforms in an ATP-competitive manner. It has an IC(50) of 3nM, and shows slight selectivity toward p110beta (11-fold) and p110gamma (25-fold).
Purity:
>95%
Signal word:
Warning
Solubility Chemicals:
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Combined CA-125 test and ultrasonography in the presurgical evaluation of ovarian mass: S.W. Chiu, et al.; Gaoxiong Yi Xue Ke Xue Za Zhi 7, 429 (1991)
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