BGT226 maleate
| Code | Size | Price |
|---|
| SYN-1178-M100 | 100 mg | Enquire |
Quantity:
| SYN-1178-M001 | 1 mg | £115.00 |
Quantity:
| SYN-1178-M005 | 5 mg | £151.00 |
Quantity:
| SYN-1178-M010 | 10 mg | £385.00 |
Quantity:
| SYN-1178-M050 | 50 mg | £1,123.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
NVP-BEZ226; BEZ-226
Appearance:
Solid.
CAS:
1245537-68-1
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C28H25F3N6O2.C4H4O4/c1-35-24-16-33-22-6-3-17(18-4-8-25(39-2)34-15-18)13-20(22)26(24)37(27(35)38)19-5-7-23(21(14-19)28(29,30)31)36-11-9-32-10-12-36;5-3(6)1-2-4(7)8/h3-8,13-16,32H,9-12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChiKey:
YUXMAKUNSXIEKN-BTJKTKAUSA-N
Long Description:
Chemical. CAS: 1245537-68-1. Formula: C28H25F3N6O2 . C4H4O4. MW: 534.5 . 116.1. NVP-BGT226 is a novel, orally bioavailable small-molecule inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin with an IC(50) of 1nM.
Molecular Formula:
C28H25F3N6O2 . C4H4O4
Molecular Weight:
534.5 . 116.1
Package Type:
Plastic Vial
Product Description:
NVP-BGT226 is a novel, orally bioavailable small-molecule inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin with an IC(50) of 1nM.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Simultaneous targeting of PI3K and mTOR with NVP-BGT226 is highly effective in multiple myeloma: P. Baumann, et al.; Anticancer Drugs 23, 131 (2012)