TAE684
| Code | Size | Price |
|---|
| SYN-1159-M100 | 100 mg | Enquire |
Quantity:
| SYN-1159-M001 | 1 mg | £115.00 |
Quantity:
| SYN-1159-M005 | 5 mg | £197.00 |
Quantity:
| SYN-1159-M010 | 10 mg | £303.00 |
Quantity:
| SYN-1159-M050 | 50 mg | £877.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
NVP-TAE684
Appearance:
Solid.
CAS:
761439-42-3
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C30H40ClN7O3S/c1-21(2)42(39,40)28-8-6-5-7-26(28)33-29-24(31)20-32-30(35-29)34-25-10-9-23(19-27(25)41-4)37-13-11-22(12-14-37)38-17-15-36(3)16-18-38/h5-10,19-22H,11-18H2,1-4H3,(H2,32,33,34,35)
InChiKey:
QQWUGDVOUVUTOY-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 761439-42-3. Formula: C30H40ClN7O3S. MW: 614.2. TAE684 is a potent and selective ALK inhibitor with an IC(50) of 3nM. It is 100-fold more sensitive for ALK over InsR.
Molecular Formula:
C30H40ClN7O3S
Molecular Weight:
614.2
Package Type:
Plastic Vial
Product Description:
TAE684 is a potent and selective ALK inhibitor with an IC(50) of 3nM. It is 100-fold more sensitive for ALK over InsR.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO or ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK: A.V. Galkin, et al.; PNAS 104, 270 (2007)
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