4-1BB Ligand Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-967-0.05mg | 0.05mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Background:
Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Background References:
- Won E.Y., et al., 2010, J. Biol. Chem. 285:9202-9210.
- Alderson M.R., et al., 1994, Eur. J. Immunol. 24:2219-2227.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Mouse 4-1BB, His Tag at 0.5 ug/mL (100 ul/well),can bind Mouse 4-1BB Ligand , Fc Tag with a linear of 0.1-3 ng/mL.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
21950
NCBI Official Name:
tumor necrosis factor ligand superfamily member 9
NCBI Official Symbol:
4-1BB Ligand
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
49 kDa
Protein Accession #:
NP_033430
Purity:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P41274