Globosuxanthone A
Product Code: AG-CN2-0174
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0174-C250 | 250 ug | £85.00 |
Quantity:
| AG-CN2-0174-M001 | 1 mg | £210.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
(1R,2R)-1,2,8-Trihydroxy-9-oxo-2,9-dihydro-1H-xanthene-1-carboxylate
Appearance:
Yellow solid.
CAS:
917091-74-8
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS06
Handling Advice:
Keep cool and dry.
InChi:
InChI=1S/C15H12O7/c1-21-14(19)15(20)10(17)6-5-9-12(15)13(18)11-7(16)3-2-4-8(11)22-9/h2-6,10,16-17,20H,1H3/t10-,15+/m1/s1
InChiKey:
HEFOWMGZUBJFBY-BMIGLBTASA-N
Long Description:
Chemical. CAS: 917091-74-8. Formula: C15H12O7. MW: 304.3. Isolated from fungus (species unknown). Potent anticancer agent. Inhibits cell growth, proliferation and survival of human tumor cells lines in vivo and in vitro. Exhibits strong cytotoxicity against a panel of human solid tumor cell lines, disrupting the cell cycle leading to the accumulation of cells in either G2/M or S phase and inducing classic signs of apoptosis. Antifungal agent against Candida albicans.
Molecular Formula:
C15H12O7
Molecular Weight:
304.3
Package Type:
Vial
Product Description:
Potent anticancer agent. Inhibits cell growth, proliferation and survival of human tumor cells lines in vivo and in vitro. Exhibits strong cytotoxicity against a panel of human solid tumor cell lines, disrupting the cell cycle leading to the accumulation of cells in either G2/M or S phase and inducing classic signs of apoptosis. Antifungal agent against Candida albicans.
Purity:
>95% (HPLC)
Signal word:
Warning
SMILES:
OC1=C2C(OC(C=C[C@@H](O)[C@]3(C(OC)=O)O)=C3C2=O)=CC=C1
Solubility Chemicals:
Soluble in ethanol, methanol or DMSO (all 1mg/ml).
Source / Host:
Isolated from fungus (species unknown).
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity: E.M.K.Wijeratne, et al.; Bioorg. Med. Chem. 14, 7917 (2006) | Absolute Configurations of Globosuxanthone A and Secondary Metabolites from Microdiplodia sp.- A Novel Solid-State CD/TDDFT Approach: H. Hussain, et al.; Eur. J. Org. Chem. 2007, 292 (2007) | A new dibenz[b,e]oxepine derivative, 1-hydroxy-10-methoxy-dibenz[b,e]oxepin-6,11-dione, from a marine-derived fungus, Beauveria bassiana TPU942; H. Yamazaki, et al.; Mar. Drugs 10, 2691 (2012) | Dihydroxanthenones from the fermentation product of an endophytic fungus Gliomastix murorum: H.Y. Yang, et al.; J. Asian Nat. Prod. Res. 17, 319 (2015)
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