Rifamycin AMP-DA
Product Code: AG-CN2-0331
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
Code | Size | Price |
---|
AG-CN2-0331-M010 | 10 mg | £120.00 |
Quantity:
AG-CN2-0331-M050 | 50 mg | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
-20°C
Images
Documents
Further Information
Alternate Names/Synonyms:
Rifamycin AMP/DA; 25-Desacetyl-AF-AMP; Deacetylrifampicin; Desacetylrifampin; 25-O-Deacetylrifampicin; 25-O-Desacetylrifampin; Rifampin-DA
Appearance:
Red powder.
CAS:
16783-99-6
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light.Protect from light when in solution.
InChi:
InChI=1S/C41H56N4O11/c1-20-11-10-12-21(2)40(53)43-31-26(19-42-45-16-14-44(8)15-17-45)36(50)28-29(37(31)51)35(49)25(6)38-30(28)39(52)41(7,56-38)55-18-13-27(54-9)22(3)33(47)24(5)34(48)23(4)32(20)46/h10-13,18-20,22-24,27,32-34,46-51H,14-17H2,1-9H3,(H,43,53)/b11-10+,18-13+,21-12-,42-19+/t20-,22+,23+,24-,27?,32-,33+,34+,41-/m0/s1
InChiKey:
KUJZTIJOBQNKDR-GFOOWPRBSA-N
Long Description:
Chemical. CAS: 16783-99-6. Formula: C41H56N4O11. MW: 780.9. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
MDL:
MFCD08063717
Molecular Formula:
C41H56N4O11
Molecular Weight:
780.9
Package Type:
Vial
Product Description:
Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.
Purity:
>95% (HPLC)
SMILES:
OC1=C(NC(/C(C)=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)O)O)=O)C(/C=N/N3CCN(C)CC3)=C(O)C4=C5C(O[C@@]2(C)C5=O)=C(C)C(O)=C41
Solubility Chemicals:
Soluble in DMSO, aqueous acetonitrile or ethanol.
Source / Host:
Semisynthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Desacetyl-rifamycins: preparation and antibacterial properties: N. Maggi, et al.; Experientia 24, 209 (1968) | Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972) | Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)
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