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Type	Category	Supplier

Popular Recombinant & Native Proteins - Abnova High purity, Animal free, Quality assured, Cost-effective, Save more with bulk order. Popular Recombinant & Native Proteins from Abnova, April 2023
Documents	Proteins	Abnova Corporation	View
MIF Monoclonal Antibody - Abnova MIF encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
Documents	Antibodies	Abnova Corporation	View
Cell Line Designation: Human Brain Microvascular Endothelial Cells (HBMEC) P0001015 Datasheet for product P0001015
Documents	Datasheets	AddexBio	View
Cloud-Clone Active Proteins Cloud-Clone Active proteins based on GMP level development, can provide a variety of specifications of protein, to meet the needs of basic science experiments, drug screening, animal drug delivery and other experiments. High Purity, Multi-species, Multi-specifications, Multi-detections
Documents	Proteins	Cloud-Clone Corp.	View
Cloud-Clone Assay Kits After 14 years of development and technology accumulation, Cloud-Clone has developed ELISA kit and CLIA kit based on enzyme linked immunoassay technology. 8,000+ kinds of high quality assay kits covering 2,000+ indicators and 10+ species are designed to assist your experimental research. Includes Sandwich ELISA Kit, Competition ELISA Kit, CLIA Kit, Antibody ELISA, Mini ELISA, Instant ELISA, High-sensitive ELISA, Wide-range ELISA.
Documents	ELISA	Cloud-Clone Corp.	View
How to conduct ELISAs- ELK Biotechnology How do you operate ELISA kits and get a satisfactory test result? What precautions should be paid attention to? Check this video recorded in ELK Biotechnologys lab!
Videos	ELISA	ELK Biotechnology	View
ELISA experiment- ELK Biotechnology ELISA experiment operation video
Videos	ELISA	ELK Biotechnology	View
ELK Biotechnology introduction ELK Biotechnology CO., LTD is manufacturer of ELISA kits, Molecular biology products and Antibodies.
Videos		ELK Biotechnology	View
Drug-Fragment Library Through structural analysis and screening of 2342 marketed drugs and 1487 clinical phase drugs, TargetMol has constructed a Drug-Fragment Library consisting of 1159 fragments.
Documents	Small Molecules	TargetMol	View
Natural Product Library A broad and diverse herbal source is an important guarantee for a high-quality Natural Product Library. TargetMol has collected massive relevant information of nearly 10,000 natural product monomers and numerous plants in 196 families, 887 genera. We can be a great help for you to search your desired compounds according to plant classifications.
Documents	Small Molecules	TargetMol	View
Compound Libraries List of compound libraries available with TargetMol
Documents	Small Molecules	TargetMol	View
Computer-Aided Drug Design
Documents		TargetMol	View
TargetMol Company Presentation Products & Services: Compound Libraries, Inhibitors & Agonists, Reagent Kits, Compound Synthesis, CADD and Recombinant Proteins.
Documents	Supplier Introduction	TargetMol	View
Drug Repurposing Drug repurposing, also known as the new use of old drugs, is a strategic approach to discover new applications for old or investigational drugs beyond their original approved applications. While the development of new drugs is a process with a high failure rate, high cost, and slow pace, repositioning old drugs for common and rare diseases is becoming increasingly attractive because of the advantages of low R&D costs and short development time.
Documents	Small Molecules	TargetMol	View
Cell Counting Kit-8 (CCK-8) The Cell Counting Kit-8 (CCK-8) utilizes the water-soluble tetrazolium salt, WST-8, to achieve rapid detection. The principle is that WST-8 can be reduced by dehydrogenases in the mitochondria to form an orange-yellow formazan in the presence of an electron coupling reagent. Through colorimetry, the number of viable cells can be dynamically quantified, thereby enabling the detection of cell proliferation or drug toxicity. The CCK-8 can be directly added to cells without the need for pre-mixing with other components, making the testing process convenient with accurate results.
Documents	Cell Based Assays	TargetMol	View
Cancer-Associated IDH1/2 Mutations from Abnova IDH1/2 Mutations
Documents	Cancer	Abnova Corporation	View
AR-V7 and Prostate Cancer from Abnova Androgen receptor (AR) is a member of the steroid receptor transcription factor family. In prostate cancer, increased levels of androgens in the tumor cells promote (1) AR signaling associated with cell-cycle regulation, growth, and survival, and (2) the expression of oncogenic fusion genes. AR-V7 is one of the splice variants of AR lacking the C-terminal LBD, but being constitutively active as a transcription factor and capable of promoting activation of target genes.
Documents	Cancer	Abnova Corporation	View
HSF1 Activation Cycle Inactive monomeric heat shock factor 1 (HSF1) exists predominantly in the cytoplasm and remains repressed by complex with regulatory proteins of HSF1 its own transcriptional targets of heat-shock protein (HSP) and cytosolic chaperonin TCP1 ring complex (TRiC). Upon a wide range of stress conditions, HSF1 is activated to undergo trimerization, nuclear translocation, and post-translational modifications (PTMs) including phosphorylation, acetylation, and sumoylation, converted into a DNA-binding-competent, active homotrimer. HSF1 is then modified by different inhibitory PTMs to cause DNA dissociation, HSF1 inactivation, and HSF1 recycling/degradation and maintained in a negative-feedback mechanism.
Documents	Antibodies	Abnova Corporation	View
Complement System ELISA Kits from Abnova Complement System ELISA Kits - Complement Components, Complement Regulators, Complement Receptors and Complement Lectin Pathway Targets from Abnova.
Documents	ELISA	Abnova Corporation	View
Popular ELISA & Assay Kits from Abnova Popular ELISA & Assay Kits
Documents	Kits	Abnova Corporation	View
Microglia Function Transition Microglia Function Transition.
Documents	Antibodies	Abnova Corporation	View
NLRP3 Inflammasome in Neurological Diseases from Abnova NLRP3 activation can occur through both potassium-dependent and potassium-independent mechanisms. Potassium-dependent mechanisms depend on potassium efflux upon MLKL activation, opening of P2X7 channel or exposure to pore-forming toxins. Potassium-independent activation is mediated through metabolic perturbation.
Documents	Inflammation	Abnova Corporation	View
Pathogenic Mechanism in Huntington's Disease Full-length mutant huntingtin (mHTT) can be further processed to generate smaller fragments and the amino-terminal HTT exon1 protein fragments are formed by aberrant splicing. Fragments can undergo self-association, oligomerization, and aggregation in the nucleus and cytoplasm, leading to the formation of inclusions that cause numerous pathogenic mechanisms, including synaptic dysregulation, mitochondrial toxicity, energy imbalance, and impaired axonal transport in Huntington’s disease.
Documents	Antibodies	Abnova Corporation	View
B Cell Receptor Associated Kinases in Lymphoma from Abnova Inhibition of BAK Activation in the Microenvironment. B cell receptor associated kinases (BAKs) are expressed in not only B cells but also other cell types, and regulate the signaling of other surface receptors within the tumor microenvironment (TME). Evidence has suggested that BAK inhibitors could disrupt the crosstalk between malignant B cells and their microenvironment by suppressing the function of BAKs in those non-tumor cells.
Documents	Kinase	Abnova Corporation	View
Transcriptional Cyclin-Dependent Kinase in Cancer from Abnova While several studies discovered the therapeutic potential of receptor tyrosine kinase (RTK) inhibition, research has recently put a spotlight on novel kinase targets that influence basal cellular process in cancer. Cyclin-dependent kinase (CDK) is one of the new areas that has been focused. As transcription-associated kinases, CDKs represent opportunities for the development of druggable targets for transcriptional-addicted cancers.
Documents	Kinase	Abnova Corporation	View

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