ProSci

CD107b Antibody [ABL-93]

Product Code:
 
PSI-99-112
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
IgG2a
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[ABL-93]
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
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Osteoclasts from ashen mice were stained with AF594 conjugated phalloidin and Rat Anti-Mouse CD107b-UNLB (Cat. No. 99-112) followed by a secondary antibody and DAPI. Images from Shimada-Sugawara M, Sakai E, Okamoto K, Fukuda M, Izumi T, Yoshida N, et al. Rab27A regulates transport of cell surface receptors modulating multinucleation and lysosome-related organelles in osteoclasts. Sci Rep. 2015;5:9620. Figure 6(a)
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Osteoclasts from ashen mice were stained with AF594 conjugated phalloidin and Rat Anti-Mouse CD107b-UNLB (Cat. No. 99-112) followed by a secondary antibody and DAPI. Images from Shimada-Sugawara M, Sakai E, Okamoto K, Fukuda M, Izumi T, Yoshida N, et al. Rab27A regulates transport of cell surface receptors modulating multinucleation and lysosome-related organelles in osteoclasts. Sci Rep. 2015;5:9620. Figure 6(a)

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PSI-99-112-0.5mg0.5mg£560.00
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Further Information

Additional Names:
LAMP-2, lysosomal-associated membrane protein 2
Application Note:
CD107b Antibody [ABL-93] for use in flow cytometry, immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, and immunoprecipitation assays.
Background:
CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. CD107b is similar in structure to Mac-1 and is expressed primarily on epithelial cells and macrophages in a variety of organs in normal and beige mutant mice.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Glycoproteins purified from BALB/c mouse embryo 3T3 cell line
NCBI Gene ID #:
16784
NCBI Official Name:
lysosomal-associated membrane protein 2
NCBI Official Symbol:
Lamp2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P17047
Research Area:
Apoptosis,Autophagy
SPECIFICITY:
CD107b
Swissprot #:
P17047
User NOte:
Optimal dilutions for each application to be determined by the researcher.