ProSci

CD11b Antibody [3A33] (FITC)

Product Code:
 
PSI-98-633
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
IgG2a
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[3A33]
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
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BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD11b-FITC (Cat. No. 98-633) and Rat Anti-Mouse Ly-6G/Ly-6C-PE .
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Frozen thermally burned mouse tissue section was stained with Rat Anti-Mouse CD11b-FITC (Cat. No. 98-633) and Rat Anti-Mouse Ly-6G/Ly-6C-PE followed by mounting with DAPI containing medium. Image from Everett J, Turner K, Cai Q, Gordon V, Whiteley M, Rumbaugh K. Arginine is a critical substrate for the pathogenesis of Pseudomonas aeruginosa in burn wound infections. MBio. 2017;8:e02160-16. Figure S1
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BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD11b-FITC (Cat. No. 98-633) and Rat Anti-Mouse Ly-6G/Ly-6C-PE .
Frozen thermally burned mouse tissue section was stained with Rat Anti-Mouse CD11b-FITC (Cat. No. 98-633) and Rat Anti-Mouse Ly-6G/Ly-6C-PE followed by mounting with DAPI containing medium. Image from Everett J, Turner K, Cai Q, Gordon V, Whiteley M, Rumbaugh K. Arginine is a critical substrate for the pathogenesis of Pseudomonas aeruginosa in burn wound infections. MBio. 2017;8:e02160-16. Figure S1

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PSI-98-633-0.5mg0.5mg£560.00
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Further Information

Additional Names:
Integrin alphaM, Mac-1alpha, Mac-1, Mo1, CR3, C3biR
Application Note:
CD11b Antibody [3A33] for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
Background:
CD11b (integrin alphaM subunit) combines with CD18 (integrin beta2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Peritoneal macrophages from B6D2 hybrid mice
NCBI Gene ID #:
16409
NCBI Official Name:
Integrin alpha M
NCBI Official Symbol:
Itgam
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P05555
Research Area:
Immunology,Neuroscience,Signal Transduction
SPECIFICITY:
CD11b
Swissprot #:
P05555
User NOte:
Optimal dilutions for each application to be determined by the researcher.