Transferrin Receptor (Extracellular domain) Antibody [TFRC/1817]
Antibody Isotype:
IgG2b, kappa
Antibody Clonality:
Monoclonal
Antibody Clone:
TFRC/1817
Applications:- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, T9, p90, CD71, Transferrin receptor protein 1, serum form, sTfR, TFRC
WB: 0.5-1 ug/ml
ELISA: 2-4 ug/ml; order the BSA free formulation for coating
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
Immunofluorescence: 1-2 ug/ml
IHC (FFPE): 1-2 ug/ml for 30 min at RT
Optimal dilution of the CD71 antibody should be determined by the researcher.
It recognizes a ~85-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This mAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
0.2 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Amino acids 94-212 (extracellular domain) of the human protein were used as the immunogen for the Transferrin Receptor / CD71 antibody.
7037
transferrin receptor
TFRC
Homo sapiens
Liquid
Protein G affinity chromatography
Cancer,Immunology,Obesity,Signal Transduction
P02786
Optimal dilutions for each application to be determined by the researcher