ProSci

Cytokeratin 18 Antibody [SB38b]

Product Code:
 
PSI-99-628
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2b
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[SB38b]
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
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Human pancreatic carcinoma cell line MIA PaCa-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (Cat. No. 99-628) followed by Donkey Anti-Mouse IgG(H+L), Multi-Species SP ads-AF555 and DAPI.
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Human carcinoma cell line HEp-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (Cat. No. 99-628) followed by Goat Anti-Mouse IgG2b, Human/Bovine/Horse SP ads-FITC and DAPI.
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Human pancreatic carcinoma cell line MIA PaCa-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (Cat. No. 99-628) followed by Donkey Anti-Mouse IgG(H+L), Multi-Species SP ads-AF555 and DAPI.
Human carcinoma cell line HEp-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (Cat. No. 99-628) followed by Goat Anti-Mouse IgG2b, Human/Bovine/Horse SP ads-FITC and DAPI.

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PSI-99-628-0.1mg0.1mg£524.00
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Further Information

Additional Names:
CK 18, keratin 18
Application Note:
Cytokeratin 18 Antibody [SB38b] for use in flow cytometry, immunocytochemistry, ELISA, western blotting assays.
Background:
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18 is a type I intermediate filament protein that exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia and is often co-expressed with cytokeratin 8. Tissues from the gastrointestinal tract, respiratory tract, and urogenital tract as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant N-terminal cytokeratin 18
NCBI Gene ID #:
3875
NCBI Official Name:
Keratin, type I cytoskeletal 18
NCBI Official Symbol:
KRT18
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P05783
Research Area:
Signal Transduction
SPECIFICITY:
Cytokeratin 18
Swissprot #:
P05783
User NOte:
Optimal dilutions for each application to be determined by the researcher.